A common feature of many solid tumors is low oxygen conditions due to inadequate blood
supply. Hypoxia induces hypoxia inducible factor (HIF) stabilization and downstream …

Tumor progression is associated with dedifferentiated histopathologies concomitant with
cancer cell survival within a changing, and often hostile, tumor microenvironment. These …

Emerging evidence has revealed that miRNAs could upregulate the expression levels of
target genes. However, the molecular mechanism underlying upregulation of targets …

Targeted DNA nanoparticles have been identified as one of the most promising nanocarriers
in anti-glioma drug delivery. We established a multifunctional nanosystem for targeted …

A novel label-free impedimetric immunosensor was fabricated for rapid, selective and
sensitive detection and quantification of Cadherin-like protein 22 (CDH22), a cancer marker …

The aggressive and highly metastatic nature of triple‐negative breast cancer (TNBC) causes
patients to suffer from the poor outcome. HIF‐1 signalling pathway is a prominent pathway …

Cell migration is essential for regulating many biological processes in physiological or
pathological conditions, including embryonic development and cancer invasion. In vitro and …

With the increasingly serious burden of osteoarthritis (OA) on modern society, it is urgent to
propose novel diagnostic biomarkers and differentiation models for OA. 7-methylguanosine …

The evolutionary origin of eukaryotes spurred the transition from prokaryotic‐like translation
to a more sophisticated, eukaryotic translation. During this process, successive gene …

A critical host response against viral infections entails the activation of innate immune
signaling that culminates in the production of antiviral proteins. DNA viruses are sensed by …