Marine natural products

JW Blunt, BR Copp, WP Hu, MHG Munro… - Natural product …, 2008 - pubs.rsc.org
Covering: 2006. Previous review: Nat. Prod. Rep., 2007, 24, 31 This review covers the
literature published in 2006 for marine natural products, with 758 citations (534 for the …

Bioactive sesterterpenes and triterpenes from marine sponges: Occurrence and pharmacological significance

SS Ebada, WH Lin, P Proksch - Marine Drugs, 2010 - mdpi.com
Marine ecosystems (> 70% of the planet's surface) comprise a continuous resource of
immeasurable biological activities and immense chemical entities. This diversity has …

Marine pharmacology in 2005–2006: Antitumour and cytotoxic compounds

AMS Mayer, KR Gustafson - European Journal of Cancer, 2008 - Elsevier
During 2005 and 2006, marine pharmacology research directed towards the discovery and
development of novel antitumour agents was reported in 171 peer-reviewed articles. The …

Application of diffusion growth chambers for the cultivation of marine sponge-associated bacteria

G Steinert, S Whitfield, MW Taylor, C Thoms… - Marine …, 2014 - Springer
Marine sponges contain dense and diverse microbial communities, which are renowned as
a source of bioactive metabolites. The biological activities of sponge-microbe natural …

Marine natural products from Indonesian waters

N Hanif, A Murni, C Tanaka, J Tanaka - Marine drugs, 2019 - mdpi.com
Natural products are primal and have been a driver in the evolution of organic chemistry and
ultimately in science. The chemical structures obtained from marine organisms are diverse …

Triterpenoids: structural diversity, biosynthetic pathway, and bioactivity

S Ghosh - Studies in natural products chemistry, 2020 - Elsevier
Triterpenoids represent C-30 scaffolds which vary from acyclic to hexacyclic and are
originated from two central C-5 isoprene precursors, isopentenyl pyrophosphate, and …

Malabaricane and isomalabaricane triterpenoids, including their glycoconjugated forms

VA Stonik, SA Kolesnikova - Marine Drugs, 2021 - mdpi.com
In this review, we discuss structural diversity, taxonomic distribution, biological activities,
biogenesis, and synthesis of a rare group of terpenoids, the so-called malabaricane and …

Looking at marine-derived bioactive molecules as upcoming anti-diabetic agents: A special emphasis on PTP1B inhibitors

SM Ezzat, MHE Bishbishy, S Habtemariam, B Salehi… - Molecules, 2018 - mdpi.com
Diabetes mellitus (DM) is a chronic metabolic disease with high morbimortality rates. DM
has two types: type 1, which is often associated with a total destruction of pancreatic beta …

Hypoglycaemic molecules for the management of diabetes mellitus from marine sources

DK Chellappan, J Chellian, NSN Rahmah… - Diabetes, Metabolic …, 2023 - Taylor & Francis
Diabetes mellitus (DM) is a chronic metabolic disorder recognized as a major health
problem globally. A defective insulin activity contributes to the prevalence and expansion of …

Total synthesis of isomalabaricane triterpenoids

YD Boyko, CJ Huck, D Sarlah - Journal of the American Chemical …, 2019 - ACS Publications
The first total syntheses of (±)-rhabdastrellic acid A and (±)-stelletin E, highly cytotoxic
isomalabaricane triterpenoids, have been accomplished in a linear sequence of 14 steps …