Adipocyte-and monocyte-mediated vicious circle of inflammation and obesity (review of cellular and molecular mechanisms)

N Todosenko, O Khaziakhmatova… - International Journal of …, 2023 - mdpi.com
Monocytes play a key role in the development of metabolic syndrome, and especially
obesity. Given the complex features of their development from progenitor cells, whose …

The regulatory role of insulin in energy metabolism and leukocyte functions

WD Cruz-Pineda, I Parra-Rojas… - Journal of leukocyte …, 2022 - academic.oup.com
Insulin is the hormone responsible for maintaining glucose homeostasis in the body, in
addition to participating in lipid metabolism, protein synthesis, and the inhibition of …

Acute strenuous exercise induces an imbalance on histone H4 acetylation/histone deacetylase 2 and increases the proinflammatory profile of PBMC of obese …

GP Dorneles, MCR Boeira, LL Schipper… - Oxidative Medicine …, 2017 - Wiley Online Library
This study evaluated the response of global histone H4 acetylation (H4ac), histone
deacetylase 2 (HDAC2) activity, as well as the production of proinflammatory cytokines and …

The exercise training modulatory effects on the obesity-induced immunometabolic dysfunctions

N Soltani, SM Marandi, M Kazemi… - … Syndrome and Obesity, 2020 - Taylor & Francis
Reduced physical activity rate in people's lifestyle is a global concern associated with the
prevalence of health disorders such as obesity and metabolic disturbance. Ample evidence …

[HTML][HTML] High-intensity interval training reduces monocyte activation in obese adults

MA de Matos, BCC Garcia, DV Vieira… - Brain, behavior, and …, 2019 - Elsevier
Alterations in the distribution and activation of monocyte subsets are frequently observed in
individuals with obesity and their participation in the pathological complications of obesity is …

Monocyte subsets in atherosclerosis and modification with exercise in humans

NH Aw, E Canetti, K Suzuki, J Goh - Antioxidants, 2018 - mdpi.com
Atherosclerosis is a progressive pathological remodeling of the arteries and one of its
hallmarks is the presence of chronic inflammation. Notably, there is an increased proportion …

The continuum of monocyte phenotypes: Experimental evidence and prognostic utility in assessing cardiovascular risk

A Cignarella, S Tedesco, R Cappellari… - Journal of leukocyte …, 2018 - academic.oup.com
The monocyte–macrophage cell lineage represents a major player in innate immunity, and
is involved in many physiologic and pathologic conditions. Particularly, monocyte …

Anti-inflammatory effect of β2 adrenergic stimulation on circulating monocytes with a pro-inflammatory state in high-fat diet-induced obesity

I Gálvez, L Martín-Cordero, MD Hinchado… - Brain, behavior, and …, 2019 - Elsevier
Obesity is a chronic condition associated with low-grade inflammation, and it also involves
alterations of the function of the hypothalamic-pituitaryadrenal axis and the sympathetic …

Brief periods of transcutaneous auricular vagus nerve stimulation improve autonomic balance and alter circulating monocytes and endothelial cells in patients with …

TL de Moraes, FO Costa, DG Cabral… - Bioelectronic …, 2023 - Springer
Background There is emerging evidence that the nervous system regulates immune and
metabolic alterations mediating Metabolic syndrome (MetS) pathogenesis via the vagus …

Monocyte adaptations in patients with obesity during a 1.5 year lifestyle intervention

ES van der Valk, DS Mulder, T Kouwenhoven… - Frontiers in …, 2022 - frontiersin.org
Background Obesity is associated with chronic, low-grade inflammation, which is reflected in
altered peripheral blood monocyte characteristics. The aim of this study was to analyze the …