Association between polymorphisms in long non-coding RNA PRNCR1 in 8q24 and risk of colorectal cancer
L Li, R Sun, Y Liang, X Pan, Z Li, P Bai, X Zeng… - Journal of Experimental …, 2013 - Springer
Background Genome-wide association studies have identified that genetic variants in 8q24
confer susceptibility to colorectal cancer (CRC). Recently, a novel lncRNA (PRNCR1) that …
confer susceptibility to colorectal cancer (CRC). Recently, a novel lncRNA (PRNCR1) that …
Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations
J He, LR Wilkens, DO Stram, LN Kolonel… - … , biomarkers & prevention, 2011 - AACR
Background: Genome-wide association studies (GWAS) in populations of European
ancestry have identified several loci that confer an increased risk of colorectal cancer (CRC) …
ancestry have identified several loci that confer an increased risk of colorectal cancer (CRC) …
Lack of APC somatic mutation is associated with early-onset colorectal cancer in African Americans
Abstract African Americans (AAs) have higher incidence and mortality rates of colorectal
cancer (CRC) compared with other US populations. They present with more right-sided …
cancer (CRC) compared with other US populations. They present with more right-sided …
Pharmacogenetic associations of the type-3 metabotropic glutamate receptor (GRM3) gene with working memory and clinical symptom response to antipsychotics in …
Rationale Type-3 metabotropic glutamate receptor gene (GRM3) single nucleotide
polymorphisms (SNPs) have been associated with cognitive performance and prefrontal …
polymorphisms (SNPs) have been associated with cognitive performance and prefrontal …
Genetic variation in vitamin D-related genes and risk of colorectal cancer in African Americans
F Pibiri, RA Kittles, RS Sandler, TO Keku… - Cancer Causes & …, 2014 - Springer
Purpose Disparities in both colorectal cancer (CRC) incidence and survival impact African
Americans (AAs) more than other US ethnic groups. Because vitamin D is thought to protect …
Americans (AAs) more than other US ethnic groups. Because vitamin D is thought to protect …
Characterization of the association between 8q24 and colon cancer: gene-environment exploration and meta-analysis
Background Genome-wide association studies and subsequent replication studies have
shown that single nucleotide polymorphisms (SNPs) in the chromosomal region 8q24 are …
shown that single nucleotide polymorphisms (SNPs) in the chromosomal region 8q24 are …
Genetic heterogeneity in colorectal cancer associations between African and European americans
BACKGROUND & AIMS: Genome-wide association studies of colorectal cancer (CRC) have
identified risk variants in 10 genomic regions. None of these studies included African …
identified risk variants in 10 genomic regions. None of these studies included African …
Susceptibility genetic variants associated with colorectal cancer risk correlate with cancer phenotype
A Abulí, X Bessa, JR González, C Ruiz–Ponte… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Ten common low-penetrant genetic variants have been
consistently associated with colorectal cancer (CRC) risk; little is known about the …
consistently associated with colorectal cancer (CRC) risk; little is known about the …
EphB2 SNPs and Sporadic Prostate Cancer Risk in African American Men
CM Robbins, S Hooker, RA Kittles, JD Carpten - PloS one, 2011 - journals.plos.org
The EphB2 gene has been implicated as a tumor suppressor gene somatically altered in
both prostate cancer (PC) and colorectal cancer. We have previously shown an association …
both prostate cancer (PC) and colorectal cancer. We have previously shown an association …
Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia
Objective Genome-wide association studies have identified a large number of single
nucleotide polymorphisms (SNPs) associated with a wide array of cancer sites. Several of …
nucleotide polymorphisms (SNPs) associated with a wide array of cancer sites. Several of …