L-Isoleucine reverses hyperammonemia-induced myotube mitochondrial dysfunction and post-mitotic senescence

A Kumar, A Bellar, S Mishra, J Sekar, N Welch… - The Journal of …, 2024 - Elsevier
Perturbations in the metabolism of ammonia, a cytotoxic endogenous metabolite, occur in a
number of chronic diseases, with consequent hyperammonemia. Increased skeletal muscle …

Exercise may promote skeletal muscle hypertrophy via enhancing leucine-sensing: preliminary evidence

Y Zhao, J Cholewa, H Shang, Y Yang, X Ding… - Frontiers in …, 2021 - frontiersin.org
Several studies have indicated a positive effect of exercise (especially resistance exercise)
on the mTOR signaling that control muscle protein synthesis and muscle remodeling …

Serum sestrin2 was lower in septic shock patients with cardiomyopathy

R Huang, F Chen, A Zeng, J Ke, S Lin - Disease Markers, 2022 - Wiley Online Library
Background. To determine the clinical significance of variations in serum sestrin2 protein
levels in the development of septic cardiomyopathy in septic shock patients. Methods. The …

[HTML][HTML] Intermittent bolus compared with continuous feeding enhances insulin and amino acid signaling to translation initiation in skeletal muscle of neonatal pigs

A Suryawan, SW El-Kadi, HV Nguyen, ML Fiorotto… - The Journal of …, 2021 - Elsevier
Background Nutrition administered as intermittent bolus feeds rather than continuously
promotes greater protein synthesis rates in skeletal muscle and enhances lean growth in a …

Responsiveness of one-carbon metabolites to a high-protein diet in older men: Results from a 10-wk randomized controlled trial

NA Gillies, AM Milan, PHP Chia, P Sharma, SM Mitchell… - Nutrition, 2021 - Elsevier
Objectives Dietary strategies to promote successful aging are divergent. Higher-protein diets
are recommended to preserve skeletal muscle mass and physical function. Conversely …

[引用][C] Impact of Age, Meal, Diet and Digestive Discomfort on B-Vitamin Bioavailability

P Sharma Ghimeray - 2021 - ResearchSpace@ Auckland

[引用][C] Optimising B Vitamin status in older adults: Exploring the role of one-carbon metabolites

NAL Gillies - 2021 - ResearchSpace@ Auckland