Recent advances in nanomaterials-based targeted drug delivery for preclinical cancer diagnosis and therapeutics
Nano-oncology is a branch of biomedical research and engineering that focuses on using
nanotechnology in cancer diagnosis and treatment. Nanomaterials are extensively …
nanotechnology in cancer diagnosis and treatment. Nanomaterials are extensively …
Exosome-based drug delivery systems and their therapeutic applications
In the past few decades, scientists have actively worked on developing effective drug
delivery systems (DDSs) as means to control life-threatening diseases and challenging …
delivery systems (DDSs) as means to control life-threatening diseases and challenging …
[HTML][HTML] Molecular polymer bottlebrushes in nanomedicine: therapeutic and diagnostic applications
M Müllner - Chemical Communications, 2022 - pubs.rsc.org
Molecular polymer bottlebrushes are densely grafted, individual macromolecules with
nanoscale proportions. The last decade has seen an increased focus on this material class …
nanoscale proportions. The last decade has seen an increased focus on this material class …
Influence of the Norbornene Anchor Group in Ru-Mediated Ring-Opening Metathesis Polymerization: Synthesis of Bottlebrush Polymers
Ring-opening metathesis polymerization (ROMP) mediated by Grubbs' third-generation
catalyst [G3,(H2IMes)(Cl) 2 (pyr) 2RuCHPh] is widely used to make bottlebrush polymers by …
catalyst [G3,(H2IMes)(Cl) 2 (pyr) 2RuCHPh] is widely used to make bottlebrush polymers by …
Multidimensional profiling of functionalized photothermal nanoplatforms for synergistic cancer immunotherapy: design, strategy, and challenge
X Wei, M Song, G Jin, W Jia, J Wang, M Liang… - Coordination Chemistry …, 2024 - Elsevier
Currently, photothermal immunotherapy (PTIT) using functionalized photothermal
nanoplatforms synergized with immune-related drugs has been shown in numerous studies …
nanoplatforms synergized with immune-related drugs has been shown in numerous studies …
[HTML][HTML] Impact of the polymer backbone chemistry on interactions of amino-acid-derived zwitterionic polymers with cells
Zwitterionic polymers are known to interact with cells and have been shown to reveal cancer
cell specificity. In this work, the importance of the chemistry of the polymer backbone for the …
cell specificity. In this work, the importance of the chemistry of the polymer backbone for the …
Impact of zwitterionic polymers on the tumor permeability of molecular bottlebrush-based nanoparticles
Biocompatible polymers possessing antifouling properties for biomolecules are necessary to
be combined with nanoparticles for cancer chemotherapy to improve their retention in blood …
be combined with nanoparticles for cancer chemotherapy to improve their retention in blood …
Nanoscale Surface Topography of Polyethylene Glycol-Coated Nanoparticles Composed of Bottlebrush Block Copolymers Prolongs Systemic Circulation and …
Improving the performance of nanocarriers remains a major challenge in the clinical
translation of nanomedicine. Efforts to optimize nanoparticle formulations typically rely on …
translation of nanomedicine. Efforts to optimize nanoparticle formulations typically rely on …
Radical–radical coupling effects in the direct-growth grafting-through synthesis of bottlebrush polymers using RAFT and ROMP
M Alaboalirat, C Vu, JB Matson - Polymer Chemistry, 2022 - pubs.rsc.org
The direct-growth technique was used to synthesize several macromonomers (MMs)
employing reversible addition–fragmentation chain transfer (RAFT) polymerization by …
employing reversible addition–fragmentation chain transfer (RAFT) polymerization by …
Solution Structure and Scaling Laws of Cylindrical and Tapered Bottlebrush Polymers
Bottlebrush polymers are a unique class of macromolecular architectures with a plethora of
potential industrial and pharmaceutical applications that critically depend on the bottlebrush …
potential industrial and pharmaceutical applications that critically depend on the bottlebrush …