Diabetic nephropathy has been traditionally diagnosed based on persistently high
albuminuria and a subsequent decline in glomerular filtration rate (GFR), which is widely …

Persistent, low‐grade inflammation is now considered a hallmark feature of chronic kidney
disease (CKD), being involved in the development of all‐cause mortality of these patients …

Aims/hypothesis The sodium–glucose cotransporter 2 (SGLT2) inhibitor canagliflozin slows
progression of kidney function decline in type 2 diabetes. The aim of this study was to …

Chronic inflammation is postulated to be involved in the development of end-stage renal
disease in diabetes, but which specific circulating inflammatory proteins contribute to this …

Despite advancements in standardizing the criteria for acute kidney injury (AKI), its definition
remains based on changes in serum creatinine and urinary output that do not specifically …

Diabetic nephropathy is a significant cause of chronic kidney disease and end-stage renal
failure globally. Much research has been conducted in both basic science and clinical …

Approximately 20% to 40% of patients with type 1 or type 2 diabetes mellitus develop
diabetic kidney disease. This is a clinical syndrome characterized by persistent albuminuria …

The current unidimensional paradigm of kidney disease detection is incompatible with the
complexity and heterogeneity of renal pathology. The diagnosis of kidney disease has …

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease globally. The
primary initiating mechanism in DN is hyperglycemia-induced vascular dysfunction, but its …

Diabetic kidney disease (DKD) remains one of the leading causes of reduced lifespan in
diabetes. The quest for both prognostic and surrogate endpoint biomarkers for advanced …