Current aspects of the endocannabinoid system and targeted THC and CBD phytocannabinoids as potential therapeutics for Parkinson's and Alzheimer's diseases: a …
Neurodegeneration leading to Parkinson's disease (PD) and Alzheimer's disease (AD) has
become a major health burden globally. Current treatments mainly target controlling …
become a major health burden globally. Current treatments mainly target controlling …
Intestinal barrier function and immune homeostasis are missing links in obesity and type 2 diabetes development
Noncommunicable diseases, such as type 2 diabetes (T2D), place a burden on healthcare
systems worldwide. The rising prevalence of obesity, a major risk factor for T2D, is mainly …
systems worldwide. The rising prevalence of obesity, a major risk factor for T2D, is mainly …
The gut microbiome, endocannabinoids and metabolic disorders
FA Iannotti, V Di Marzo - Journal of Endocrinology, 2021 - joe.bioscientifica.com
Two complex systems are emerging as being deeply involved in the control of energy
metabolism. The intestinal microbiota, with its warehouse of genes, proteins and small …
metabolism. The intestinal microbiota, with its warehouse of genes, proteins and small …
[HTML][HTML] Intervention of five strains of Lactobacillus on obesity in mice induced by high-fat diet
M Wang, B Zhang, J Hu, S Nie, T Xiong… - Journal of Functional …, 2020 - Elsevier
The intervention effect of five Lactobacillus strains on the high-fat diet induced obese
C57BL/6J mice was investigated. C57BL/6J mice were randomly divided into normal diet …
C57BL/6J mice was investigated. C57BL/6J mice were randomly divided into normal diet …
What role does the endocannabinoid system play in the pathogenesis of obesity?
P Schulz, S Hryhorowicz, AM Rychter, A Zawada… - Nutrients, 2021 - mdpi.com
The endocannabinoid system (ECS) is an endogenous signaling system formed by specific
receptors (cannabinoid type 1 and type 2 (CB1 and CB2)), their endogenous ligands …
receptors (cannabinoid type 1 and type 2 (CB1 and CB2)), their endogenous ligands …
NAPE-PLD in the ventral tegmental area regulates reward events, feeding and energy homeostasis
The N-acyl phosphatidylethanolamine-specific phospholipase D (NAPE-PLD) catalyzes the
production of N-acylethanolamines (NAEs), a family of endogenous bioactive lipids, which …
production of N-acylethanolamines (NAEs), a family of endogenous bioactive lipids, which …
Genetic contributions to the etiology of anorexia nervosa: New perspectives in molecular diagnosis and treatment
Background Anorexia nervosa is a multifactorial eating disorder that manifests with self‐
starvation, extreme anxiety, hyperactivity, and amenorrhea. Long‐term effects include organ …
starvation, extreme anxiety, hyperactivity, and amenorrhea. Long‐term effects include organ …
FAAH rs324420 Polymorphism: Biological Pathways, Impact on Elite Athletic Performance and Insights for Sport Medicine
Gene variation linked to physiological functions is recognised to affect elite athletic
performance by modulating training and competition-enabling behaviour. The fatty acid …
performance by modulating training and competition-enabling behaviour. The fatty acid …
The endocannabinoid system in pediatric inflammatory and immune diseases
M Argenziano, C Tortora, G Bellini, A Di Paola… - International journal of …, 2019 - mdpi.com
Endocannabinoid system consists of cannabinoid type 1 (CB1) and cannabinoid type 2
(CB2) receptors, their endogenous ligands, and the enzymes responsible for their synthesis …
(CB2) receptors, their endogenous ligands, and the enzymes responsible for their synthesis …
Association between the FAAH C385A variant (rs324420) and obesity-related traits: a systematic review
OD Lopez-Cortes, F Trujillo-Sanchez… - International Journal of …, 2024 - nature.com
Background Overweight and obesity are the consequence of a sustained positive energy
balance. Twin studies show high heritability rates pointing to genetics as one of the principal …
balance. Twin studies show high heritability rates pointing to genetics as one of the principal …