Current evidence suggests that severity and mortality of COVID-19 is higher in men than in
women, whereas women might be at increased risk of COVID-19 reinfection and …

Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control
study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis …

Background Obesity rates are increasing worldwide. Obesity leads to many complications,
including predisposing individuals to the development of cognitive impairment as they age …

Obesity, prediabetes, and diabetes are growing in prevalence worldwide. These metabolic
disorders are associated with neurodegenerative diseases, particularly Alzheimer's disease …

Understanding sex differences in immunological responses in the context of obesity is
important to improve health outcomes. This systematic review aimed to investigate sex …

Introduction The prevalence of obesity, prediabetes, and diabetes continues to grow
worldwide. These metabolic dysfunctions predispose individuals to neurodegenerative …

Peripheral neuropathy (PN) is a severe complication that affects over 30% of prediabetic
and 60% of type 2 diabetic (T2D) patients. The metabolic syndrome is increasingly …

CRISPR-Cas9-mediated leptin (Lep) knockout (KO) mice exhibited prominent phenotypes
for constipation, even though they were not compared with other model animals. This study …

ABSTRACT International Women's Day 2024 has a theme of inclusion. As publishers of
preclinical research, we aim to show how inclusion of females in research advances …

Obesity is an epidemic, and it is characterized by a state of low-grade systemic inflammation.
A key component of inflammation is the activation of inflammasomes, multiprotein …