A mitochondrial nanoguard modulates redox homeostasis and bioenergy metabolism in diabetic peripheral neuropathy

Y Yao, X Lei, Y Wang, G Zhang, H Huang, Y Zhao… - ACS …, 2023 - ACS Publications
As a major late complication of diabetes, diabetic peripheral neuropathy (DPN) is the
primary reason for amputation. Nevertheless, there are no wonder drugs available …

Nucleic acid nanomaterials-based therapy for osteoarthritis: Progress and prospects

Y Yao, M Yang, S Shi - Current Drug Metabolism, 2023 - ingentaconnect.com
Osteoarthritis (OA) involves lesions of the entire joint and remains one of the health
problems plaguing the world. The pathological mechanism of OA is complex and involves …

Multifunctional DNA Tetrahedron for Alzheimer's Disease Mitochondria-Targeted Therapy by MicroRNA Regulation

W Li, X Peng, X Mei, M Dong, Y Li… - ACS Applied Materials & …, 2023 - ACS Publications
The principal hallmark of Alzheimer's disease (AD) is neuron mitochondrial dysfunction,
whereas mitochondrial miRNAs potentially play important roles. Nevertheless, efficacious …

Albumin-coated framework nucleic acids as bionic delivery system for triple-negative breast cancer therapy

Y Zhang, C Mao, Y Zhan, Y Zhao… - ACS Applied Materials …, 2022 - ACS Publications
Triple-negative breast cancer (TNBC) is a subtype of breast cancer, and it has aggressive
and more frequent tissue metastases than other breast cancer subtypes. Because the …

Multifunctional architectures of cyclic dipeptide copolymers and composites, and modulation of multifaceted amyloid-β toxicity

H Moorthy, LP Datta, S Samanta… - ACS Applied Materials …, 2022 - ACS Publications
Alzheimer's disease (AD) is a major neurodegenerative disorder primarily characterized by
the β-amyloid (Aβ42) misfolding and aggregation-associated multifaceted amyloid toxicity …

Application of Nucleic Acid Nanomaterials in the Treatment of Endocrine and Metabolic Diseases

Q Zhu, Y Xie, T Fu, C Shi, L Bai, L Liu… - Current Drug …, 2023 - ingentaconnect.com
Endocrine and metabolic diseases are the most prevalent chronic diseases globally, posing
the greatest hazard to human health. Although various medications are applied in treating …

Early-relief effects of tetrahedral DNA nanostructures-assisted depression therapy via modulates hippocampal neurogenesis and neuroplasticity

Y Dou, X Yang, Y Du, W Cui, Y Luo, J Wei… - Chemical Engineering …, 2024 - Elsevier
The delayed-onset effects of antidepressants may increase the risk of suicide in patients
before they take full effect. Accumulating evidence indicates that the restriction of the blood …

Framework Nucleic Acid Nanomaterial‐Based Therapy for Osteoarthritis: Progress and Prospects

Y Yao, H Huang, S Shi - Nucleic Acid‐Based Nanomaterials …, 2024 - Wiley Online Library
Osteoarthritis (OA) includes lesions of the whole joint and remains one of the health
problems that baffle the world. The pathological mechanism of OA is complex and involves …

Application of Framework Nucleic Acid‐Based Nanomaterials in the Treatment of Endocrine and Metabolic Diseases

J Xiao - Nucleic Acid‐Based Nanomaterials: Stabilities and …, 2024 - Wiley Online Library
Endocrine and metabolic diseases are the most prevalent chronic diseases globally, posing
the greatest hazard to human health. Although various medications are applied in treating …