According to Quality by Design (QbD) concept, quality should be built into product/method
during pharmaceutical/analytical development. Usually, there are many input factors that …

Cancer is a life-threatening disease killing millions of people globally. Among various
medical treatments, nano-medicines are gaining importance continuously. Many …

Introduction and objective Previous studies indicate that miltefosine (MFS) may be an
alternative as an antifungal agent; however, it presents several adverse effects. Thus, the …

Objective The purpose of this study was to develop novel carbopol-based miltefosine-
loaded transfersomal gel (HePCTG) for the treatment of cutaneous leishmaniasis (CL) via …

Breast cancer is among the most common types of cancer in women and it is the cause of a
high rate of mortality globally. The use of anticancer drugs is the standard treatment …

Antimicrobial photodynamic therapy (aPDT) is promising for oral decontamination. Curcumin
has been used as photosensitizer; however, the hydrophobic properties can negatively …

Abstract Systems composed of bioadhesive and thermoresponsive polymers can combine in
situ gelation with bio/mucoadhesion, enhancing retention of topically applied drugs. The …

The widespread push to invest in local cancer therapies comes from the need to overcome
the limitations of systemic treatment options. In contrast to intravenous administration, local …

Micelle drugs based on a polymeric platform offer great advantages over liposomal drugs for
tumor treatment. Although nearly all of the nanomedicines approved in the clinical use can …

Objectives To develop alginate nanoparticles functionalized with polysorbate 80 (P80) as
miltefosine carriers for brain targeting in the oral treatment of cryptococcal meningitis …