Post-transcriptional control of haemostatic genes: mechanisms and emerging therapeutic concepts in thrombo-inflammatory disorders

S Danckwardt, DA Trégouët… - Cardiovascular …, 2023 - academic.oup.com
The haemostatic system is pivotal to maintaining vascular integrity. Multiple components
involved in blood coagulation have central functions in inflammation and immunity. A …

[HTML][HTML] Isomirs–hidden soldiers in the mirna regulatory army, and how to find them?

I Glogovitis, G Yahubyan, T Würdinger… - Biomolecules, 2020 - mdpi.com
Numerous studies on microRNAs (miRNA) in cancer and other diseases have been
accompanied by diverse computational approaches and experimental methods to predict …

Unification of miRNA and isomiR research: the mirGFF3 format and the mirtop API

T Desvignes, P Loher, K Eilbeck, J Ma, G Urgese… - …, 2020 - academic.oup.com
Motivation MicroRNAs (miRNAs) are small RNA molecules (∼ 22 nucleotide long) involved
in post-transcriptional gene regulation. Advances in high-throughput sequencing …

[HTML][HTML] Paired-end small RNA sequencing reveals a possible overestimation in the isomiR sequence repertoire previously reported from conventional single read …

JF Sanchez Herrero, R Pluvinet, A Luna de Haro… - BMC …, 2021 - Springer
Background Next generation sequencing has allowed the discovery of miRNA isoforms,
termed isomiRs. Some isomiRs are derived from imprecise processing of pre-miRNA …

Extracellular microRNA 3'end modification across diverse body fluids

K Koyano, JH Bahn, X Xiao - Epigenetics, 2021 - Taylor & Francis
ABSTRACT microRNAs (miRNAs) are small non-coding RNAs that play critical roles in gene
regulation. The presence of miRNAs in extracellular biofluids is increasingly recognized …

Bayesian network analysis of plasma microRNA sequencing data in patients with venous thrombosis

F Thibord, G Munsch, C Perret, P Suchon… - European Heart …, 2020 - academic.oup.com
MicroRNAs (miRNAs) are small regulatory RNAs participating to several biological
processes and known to be involved in various pathologies. Measurable in body fluids …

isomiRs-specific differential expression is the rule, not the exception: Are we missing hundreds of species in microRNA analysis?

E Schmauch, P Laitinen, TA Turunen, MA Väänänen… - bioRxiv, 2021 - biorxiv.org
MicroRNAs (miRNAs) are small RNA molecules that act as regulators of gene expression
through targeted mRNA degradation. They are involved in many biological and …

[PDF][PDF] Caractérisation de la régulation génétique des microARN plasmatiques en grossesse et leur potentielle implication dans le développement du diabète …

F White - 2022 - savoirs.usherbrooke.ca
SOMMAIRE L'arrivée de nouvelles techniques de séquençage à haut débit a procuré une
puissante façon d'étudier le génome humain. Parallèlement, le développement d'outils bio …

[HTML][HTML] The intricacies of isomiRs: from classification to clinical relevance

V Wagner, E Meese, A Keller - Trends in Genetics, 2024 - cell.com
MicroRNAs (miRNAs) and isoforms of their archetype, called isomiRs, regulate gene
expression via complementary base-pair binding to messenger RNAs (mRNAs). The …