The study of homologous recombination has its historical roots in meiosis. In this context,
recombination occurs as a programmed event that culminates in the formation of crossovers …

Gene conversion, one of the two mechanisms of homologous recombination, involves the
unidirectional transfer of genetic material from a'donor'sequence to a highly homologous' …

At the final step of homologous recombination, Holliday junction-containing joint molecules
(JMs) are resolved to form crossover or noncrossover products. The enzymes responsible …

The efficient and timely resolution of DNA recombination intermediates is essential for
bipolar chromosome segregation. Here, we show that the specialized chromosome …

The RecQ helicases are conserved from bacteria to humans and play a critical role in
genome stability. In humans, loss of RecQ gene function is associated with cancer …

Crossing-over ensures accurate chromosome segregation during meiosis, and every pair of
chromosomes obtains at least one crossover, even though the majority of recombination …

The BLM helicase has been shown to maintain genome stability by preventing accumulation
of aberrant recombination intermediates. We show here that the Saccharomyces cerevisiae …

Accurate segregation of homologous chromosomes during meiosis depends on the ability of
meiotic cells to promote reciprocal exchanges between parental DNA strands, known as …

Faithful segregation of homologous chromosomes (homologs) during meiosis depends on
chiasmata which correspond to crossovers between parental DNA strands. Crossover …

Meiotic crossovers (COs) have two important roles, shuffling genetic information and
ensuring proper chromosome segregation. Despite their importance and a large excess of …