Endocytosis is a critical step in the process by which many therapeutic nanomedicines reach
their intracellular targets. Our understanding of cellular uptake mechanisms has developed …

Endocytosis is a complex process whereby cell surface proteins, lipids and fluid from the
extracellular environment are packaged, sorted and internalized into cells. Endocytosis is …

Macropinocytosis is a unique pathway of endocytosis characterised by the nonspecific
internalisation of large amounts of extracellular fluid, solutes and membrane in large …

Endocytic mechanisms control the lipid and protein composition of the plasma membrane,
thereby regulating how cells interact with their environments. Here, we review what is known …

Macropinocytosis is a regulated form of endocytosis that mediates the non‐selective uptake
of solute molecules, nutrients and antigens. It is an actin‐dependent process initiated from …

Macropinocytosis is differentiated from other types of endocytosis by its unique susceptibility
to inhibitors of Na+/H+ exchange. Yet, the functional relationship between Na+/H+ exchange …

Although viruses are simple in structure and composition, their interactions with host cells
are complex. Merely to gain entry, animal viruses make use of a repertoire of cellular …

The cell imposes multiple barriers to virus entry. However, viruses exploit fundamental
cellular processes to gain entry to cells and deliver their genetic cargo. Virus entry pathways …

Endocytosis occurs at the cell surface and involves internalization of the plasma membrane
(PM) along with its constituent membrane proteins and lipids. Endocytosis is involved in …

As obligatory intracellular parasites, viruses rely on host-cell functions for most aspects of
their replication cycle. This is born out during entry, when most viruses that infect vertebrate …