This systematic review summarizes pharmacogenetic studies on antidepressant response
and side effects. Out of the 17 genes we reviewed, 8 genes were entered into the meta …

Arginine vasopressin (AVP) and oxytocin (OXT) are social hormones and mediate affiliative
behaviors in mammals and as recently demonstrated, also in humans. There is intense …

Mendelian randomization is the use of genetic instrumental variables to obtain causal
inferences from observational data. Two recent developments for combining information on …

IgA nephropathy (IgAN), major cause of kidney failure worldwide, is common in Asians,
moderately prevalent in Europeans, and rare in Africans. It is not known if these differences …

Replication helps ensure that a genotype-phenotype association observed in a genome-
wide association (GWA) study represents a credible association and is not a chance finding …

Background Asthma is a complex disease that has genetic and environmental causes. The
genetic factors associated with susceptibility to asthma remain largely unknown. Methods …

Dyslexia (or reading disability) and specific language impairment (or SLI) are common
childhood disorders that show considerable co-morbidity and diagnostic overlaps and have …

Associations of oxytocin receptor gene (OXTR) variants and autism spectrum disorders
(ASD) have been reported in earlier studies; in one of the studies associations with IQ and …

Sex differences in the genetic epidemiology and clinical features of psychiatric disorders are
well recognized, but the individual genes contributing to these effects have rarely been …

Abstract Objective: White matter hyperintensities (WMHs) detectable by magnetic resonance
imaging are part of the spectrum of vascular injury associated with aging of the brain and are …