Oxidative stress in ageing and chronic degenerative pathologies: molecular mechanisms involved in counteracting oxidative stress and chronic inflammation

TS Leyane, SW Jere, NN Houreld - International journal of molecular …, 2022 - mdpi.com
Ageing and chronic degenerative pathologies demonstrate the shared characteristics of
high bioavailability of reactive oxygen species (ROS) and oxidative stress, chronic/persistent …

The role of vitamin K in humans: implication in aging and age-associated diseases

DS Popa, G Bigman, ME Rusu - Antioxidants, 2021 - mdpi.com
As human life expectancy is rising, the incidence of age-associated diseases will also
increase. Scientific evidence has revealed that healthy diets, including good fats, vitamins …

Phytofabricated metallic nanoparticles and their clinical applications

A Baranwal, K Mahato, A Srivastava, PK Maurya… - RSC …, 2016 - pubs.rsc.org
Metallic nanoparticles (MNPs) have seen myriad applications in various fields of science
and technology. Green chemistry based NP synthesis offers several advantages over …

The nutraceuticals as modern key to achieve erythrocyte oxidative stress fighting in osteoarthritis

A Mariano, I Bigioni, F Misiti, L Fattorini… - Current issues in …, 2022 - mdpi.com
Osteoarthritis (OA), the most common joint disease, shows an increasing prevalence in the
aging population in industrialized countries. OA is characterized by low-grade chronic …

Major involvement of bacterial components in rheumatoid arthritis and its accompanying oxidative stress, systemic inflammation and hypercoagulability

E Pretorius, OO Akeredolu, P Soma… - … biology and medicine, 2017 - journals.sagepub.com
We review the evidence that infectious agents, including those that become dormant within
the host, have a major role to play in much of the etiology of rheumatoid arthritis and the …

Inhibition of erythrocyte's catalase, glutathione peroxidase or peroxiredoxin 2–Impact on cytosol and membrane

D Melo, S Coimbra, S Rocha, A Santos-Silva - Archives of Biochemistry …, 2023 - Elsevier
Abstract Catalase (CAT), glutathione peroxidase (GPx) and Prx2 (peroxiredoxin 2) are the
main antioxidant enzymatic defenses of erythrocytes. They prevent and minimize oxidative …

7β-Hydroxycholesterol and 7-ketocholesterol: New oxidative stress biomarkers of sarcopenia inducing cytotoxic effects on myoblasts and myotubes

I Ghzaiel, A Zarrouk, V Pires, JPP de Barros… - The Journal of Steroid …, 2023 - Elsevier
Aging is a complex biological process which can be associated with skeletal muscle
degradation leading to sarcopenia. The aim of this study consisted i) to determine the …

Red blood cells as an efficient in vitro model for evaluating the efficacy of metallic nanoparticles

R Wadhwa, T Aggarwal, N Thapliyal, A Kumar, Priya… - 3 Biotech, 2019 - Springer
Blood and the linings of blood vessels may be regarded as a fifth tissue type. The human
body contains 5× 10 9 red blood cells (RBCs) per ml, a total of 2.5× 10 13 cells in the 5 l of …

The pivotal role of oxidative stress in the pathophysiology of cardiovascular-renal remodeling in kidney disease

V Ravarotto, G Bertoldi, G Innico, L Gobbi, LA Calò - Antioxidants, 2021 - mdpi.com
The excessive activation of the renin-angiotensin system in kidney disease leads to
alteration of intracellular pathways which concur altogether to the induction of …

Nano-bioengineered sensing technologies for real-time monitoring of reactive oxygen species in in vitro and in vivo models

R Kumari, DS Dkhar, S Mahapatra, R Kumar… - Microchemical …, 2022 - Elsevier
Reactive oxygen species are produced as a by-product of the animal cellular metabolism
and play an important function in cell signaling. Uncontrolled reactive oxygen species …