Progesterone actions and resistance in gynecological disorders
JA MacLean, K Hayashi - Cells, 2022 - mdpi.com
Estrogen and progesterone and their signaling mechanisms are tightly regulated to maintain
a normal menstrual cycle and to support a successful pregnancy. The imbalance of estrogen …
a normal menstrual cycle and to support a successful pregnancy. The imbalance of estrogen …
Niclosamide targets the dynamic progression of macrophages for the resolution of endometriosis in a mouse model
Due to the vital roles of macrophages in the pathogenesis of endometriosis, targeting
macrophages could be a promising therapeutic direction. Here, we investigated the efficacy …
macrophages could be a promising therapeutic direction. Here, we investigated the efficacy …
Escherichia coli inhibits endometriosis by inducing M1 polarity of peritoneal macrophages and the IL-1 signaling pathway
S Yan, Y Huang, L Xu, X Dong, S Wang… - Molecular Human …, 2023 - academic.oup.com
The development of endometriosis is closely linked to macrophages, and the type M1
macrophage has been hypothesized to play an inhibitory role in its progression. Escherichia …
macrophage has been hypothesized to play an inhibitory role in its progression. Escherichia …
The involvement of peritoneal GATA6+ macrophages in the pathogenesis of endometriosis
Endometriosis is a chronic inflammatory disease that causes debilitating pelvic pain in
women. Macrophages are considered to be key players in promoting disease progression …
women. Macrophages are considered to be key players in promoting disease progression …
High-fat diets promote peritoneal inflammation and augment endometriosis-associated abdominal hyperalgesia
T Herup-Wheeler, M Shi, ME Harvey… - Frontiers in …, 2024 - frontiersin.org
Immune dysfunction is one of the central components in the development and progression of
endometriosis by establishing a chronic inflammatory environment. Western-style high-fat …
endometriosis by establishing a chronic inflammatory environment. Western-style high-fat …
Endometrial epithelial ARID1A is required for uterine immune homeostasis during early pregnancy
RM Marquardt, SH Ahn, JJ Reske, RL Chandler… - International Journal of …, 2022 - mdpi.com
A growing body of work suggests epigenetic dysregulation contributes to endometriosis
pathophysiology and female infertility. The chromatin remodeling complex subunit AT-rich …
pathophysiology and female infertility. The chromatin remodeling complex subunit AT-rich …
Die Wirkung drei neuer Substanzen auf mesenchymale Stamm-/Stromazellen in der lokalen und systemischen Inflammation
MS Kállai - 2024 - publikationen.ub.uni-frankfurt.de
In Deutschland leidet ca. jeder zehnte Mensch über 40 Jahren an einer chronischen
Einschränkung seiner Nierenfunktion. Nicht wenige davon sind im Laufe der Erkrankung auf …
Einschränkung seiner Nierenfunktion. Nicht wenige davon sind im Laufe der Erkrankung auf …
[图书][B] High-Fat Diets Promote Peritoneal Inflammation and Aggravate Endometriosis-Associated Pain in a Mouse Model of Endometriosis
T Herup-Wheeler - 2023 - search.proquest.com
Endometriosis is a chronic inflammatory disease with a complex symptomatic and
pathobiological nature that affects about 10% of reproductive-aged women. It is a condition …
pathobiological nature that affects about 10% of reproductive-aged women. It is a condition …
The NLRP3 activation-related signature predict the diagnosis and indicate immune characteristics in endometriosis
W Nong, H Wei, S Dou, L He, T Li, L Lin, B Wei… - 2023 - researchsquare.com
Endometriosis (EMS) is a common gynecological disease leading to chronic pelvic pain and
infertility in women of reproductive age, but its underlying pathogenic genes and effective …
infertility in women of reproductive age, but its underlying pathogenic genes and effective …
Niclosamide targets macrophages to rescue the disrupted peritoneal homeostasis in endometriosis
Due to the vital roles of macrophages in the pathogenesis of endometriosis, targeting
macrophages could be a new therapeutic direction. Here, we investigated the efficacy of …
macrophages could be a new therapeutic direction. Here, we investigated the efficacy of …