Acute pancreatitis (AP) is an inflammatory disease of the pancreas, which can progress to
severe AP, with a high risk of death. It is one of the most complicated and clinically …

Background Japanese (JPN) guidelines for the management of acute pancreatitis were
published in 2006. The severity assessment criteria for acute pancreatitis were later revised …

Objective To provide guidelines for the management of the intensive care patient with
severe acute pancreatitis. Design A consensus committee of 22 experts was convened. A …

Severe acute pancreatitis (SAP), which is the most serious type of this disorder, is
associated with high morbidity and mortality. SAP runs a biphasic course. During the first 1-2 …

Guidelines for the diagnosis and treatment of acute pancreatitis were published by the
American College of Gastroenterology in 1997 (1). These and subsequent guidelines (2–7) …

Septic shock, the most severe complication of sepsis, is a deadly disease. In recent years,
exciting advances have been made in the understanding of its pathophysiology and …

Mild acute pancreatitis is not an indication for pancreatic surgery.(2) The use of prophylactic
broad-spectrum antibiotics reduces infection rates in computed tomography-proven …

Background Pancreatic necrosis may complicate severe acute pancreatitis, and is
detectable by computed tomography (CT). If it becomes infected mortality increases, but the …

Background & Aims: Antibiotic prophylaxis in necrotizing pancreatitis remains controversial.
Until now, there have been no double-blind studies dealing with this topic. Methods: A total …

Background & Aims: In patients with severe, necrotizing pancreatitis, it is common to
administer early, broad-spectrum antibiotics, often a carbapenem, in the hope of reducing …