[HTML][HTML] Proactive and reactive roles of TGF-β in EMT-induced plasticity
Cancer cells adapt to varying stress conditions to survive through plasticity. Stem cells
exhibit a high degree of plasticity, allowing them to generate more stem cells or differentiate …
exhibit a high degree of plasticity, allowing them to generate more stem cells or differentiate …
Autophagy and breast cancer: connected in growth, progression, and therapy
Q Wu, D Sharma - Cells, 2023 - mdpi.com
Despite an increase in the incidence of breast cancer worldwide, overall prognosis has
been consistently improving owing to the development of multiple targeted therapies and …
been consistently improving owing to the development of multiple targeted therapies and …
A synthetic metastatic niche reveals antitumor neutrophils drive breast cancer metastatic dormancy in the lungs
Biomaterial scaffolds mimicking the environment in metastatic organs can deconstruct
complex signals and facilitate the study of cancer progression and metastasis. Here we …
complex signals and facilitate the study of cancer progression and metastasis. Here we …
Dormancy in breast cancer
E Dalla, A Sreekumar… - Cold Spring …, 2023 - perspectivesinmedicine.cshlp.org
The pattern of delayed recurrence in a subset of breast cancer patients has long been
explained by a model that incorporates a variable period of cellular or tumor mass dormancy …
explained by a model that incorporates a variable period of cellular or tumor mass dormancy …
Oncobiology and treatment of breast cancer in young women
R Kumar, C Abreu, M Toi, S Saini, S Casimiro… - Cancer and Metastasis …, 2022 - Springer
Female breast cancer emerged as the leading cancer type in terms of incidence globally in
2020. Although mortality due to breast cancer has improved during the past three decades …
2020. Although mortality due to breast cancer has improved during the past three decades …
GRHL2 motif is associated with intratumor heterogeneity of cis-regulatory elements in luminal breast cancer
K Kumegawa, Y Takahashi, S Saeki, L Yang… - NPJ Breast …, 2022 - nature.com
In breast cancer patients, tumor heterogeneity is associated with prognosis and therapeutic
response; however, the epigenetic diversity that exists in primary tumors remains unknown …
response; however, the epigenetic diversity that exists in primary tumors remains unknown …
[HTML][HTML] Dormant tumors circumvent tumor-specific adaptive immunity by establishing a Treg-dominated niche via DKK3
TN Trotter, CE Dagotto, D Serra, T Wang, X Yang… - JCI insight, 2023 - ncbi.nlm.nih.gov
Approximately 30% of breast cancer survivors deemed free of disease will experience
locoregional or metastatic recurrence even up to 30 years after initial diagnosis, yet how …
locoregional or metastatic recurrence even up to 30 years after initial diagnosis, yet how …
Extracellular vesicles in breast cancer: from biology and function to clinical diagnosis and therapeutic management
S Loric, JA Denis, C Desbene, M Sabbah… - International journal of …, 2023 - mdpi.com
Breast cancer (BC) is the first worldwide most frequent cancer in both sexes and the most
commonly diagnosed in females. Although BC mortality has been thoroughly declining over …
commonly diagnosed in females. Although BC mortality has been thoroughly declining over …
Vessel co-option and angiotropic extravascular migratory metastasis: a continuum of tumour growth and spread?
Two fields of cancer research have emerged dealing with the biology of tumour cells
localised to the abluminal vascular surface: vessel co-option (VCo), a non-angiogenic mode …
localised to the abluminal vascular surface: vessel co-option (VCo), a non-angiogenic mode …
Onco-Breastomics: An Eco-Evo-Devo Holistic Approach
Known as a diverse collection of neoplastic diseases, breast cancer (BC) can be
hyperbolically characterized as a dynamic pseudo-organ, a living organism able to build a …
hyperbolically characterized as a dynamic pseudo-organ, a living organism able to build a …