MALT lymphoma is an extranodal B-cell lymphoma of the marginal zone of mucosa-
associated lymphoid tissue (MALT), caused by malignant transformation of B-cells in the …

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with a notably poor
prognosis. A large number of patients with PDAC develop metastases before they are …

Background Programmed death-ligand-1 (PD-L1) molecule is a well-known predictive
biomarker for the efficacy of immune checkpoint inhibitors (ICIs) in several cancers. Present …

There has been an increasing use of master protocols in oncology clinical trials because of
its efficiency to accelerate cancer drug development and flexibility to accommodate multiple …

Introduction The year 2021 will be remembered as a transformational year in the
management of both esophageal and gastric cancers. Decades of failed clinical trials had …

In the West, recent decades have demonstrated an epidemiological trend towards esophago-
gastric adenocarcinomas (EGAC), with considerable associated mortality. Historically …

Regardless of success of immunotherapy in other tumor types, pancreatic ductal
adenocarcinoma (PDAC) has remained largely resistant to the benefit of immunotherapy …