Abstract The Renal Tumour Study Group of the International Society of Paediatric Oncology
(SIOP–RTSG) has developed a new protocol for the diagnosis and treatment of childhood …

Wilms' tumor is the commonest renal tumor of childhood affecting one in 10,000 children. It is
also one of the successes of paediatric oncology with long term survival above 90% for …

Background Before this study started, the standard postoperative chemotherapy regimen for
stage II–III Wilms' tumour pretreated with chemotherapy was to include doxorubicin …

Background Wilms tumor accounts for more than 90% of all malignant kidney neoplasms in
children. Survival after diagnosis and treatment is excellent in most high-income countries …

In Europe, almost 1000 children are diagnosed with a malignant renal tumour each year.
The vast majority of cases are nephroblastoma, also known as Wilms' tumour (WT). Most …

In the International Society of Paediatric Oncology renal tumour trials, preoperative
chemotherapy has been successfully applied with resulting reduction of tumour rupture and …

Background The National Wilms Tumor Study (NWTS) approach to treating stage III
favorable-histology Wilms tumor (FHWT) is Regimen DD4A (vincristine, dactinomycin, and …

Background To review the clinical characteristics and survival of infants diagnosed with a
primary renal tumor in the first 7 months of life. Procedure A retrospective data review of …

Background Survival data of malignant rhabdoid tumour of the kidney (MRTK) registered in
SIOP trials, advocating preoperative chemotherapy, are not available. Aim To evaluate …

Survival for patients with Wilms' tumor when considered as a whole, once less than 30%, is
currently greater than 90%, with this dramatic improvement being due, in part, to the …