Monoterpenoids are C10 isoprenoid natural products with diverse functions as volatile and
non-volatile secondary metabolites. Their biosynthesis from acyclic diphosphate precursors …

Abstract The genus Salvia L.(Lamiaceae) comprises myriad distinct medicinal herbs, with
terpenoids as one of their major active chemical groups. Abietane-type diterpenoids (ATDs) …

Highlights•Plant natural products are a source of established and novel pharmaceuticals.•To
access the full diversity requires understanding of biosynthetic origins.•Co-expression is a …

Plants produce a staggering array of chemicals that are the basis for organismal function
and important human nutrients and medicines. However, it is poorly defined how these …

Mitragyna speciosa (“kratom”) is used as a natural remedy for pain and management of
opioid dependence. The pharmacological properties of kratom have been linked to a …

Highlights•Challenges in pathway discovery of plant natural products (PNPs).•Multiomics-
guided pathway prediction strategies and tools.•Biochemical characterization of putative …

Iridoids are non‐canonical monoterpenoids produced by both insects and plants. An
example is the cat‐attracting and insect‐repelling volatile iridoid nepetalactone, produced …

Rehmannia glutinosa, a member of the Scrophulariaceae family, has been widely used in
traditional Chinese medicine since ancient times. The main bioactive component of R …

Phlomoides rotata is a traditional Chinese herbal medicine that grows in the Qinghai–Tibet
Plateau region at a 3100–5000 m altitude. Iridoid compounds are the main active …

Plants produce a staggering array of chemicals that are the basis for organismal function
and diversity and also provide essential human nutrients and medicine. However, it is poorly …