Natural antioxidant activities of plants in preventing cataractogenesis

E Imelda, R Idroes, K Khairan, RR Lubis, AH Abas… - Antioxidants, 2022 - mdpi.com
A cataract is a condition that causes 17 million people to experience blindness and is the
most significant cause of vision loss, around 47.9%. The formation of cataracts is linked to …

Reversible cold-induced lens opacity in a hibernator reveals a molecular target for treating cataracts

H Yang, X Ping, J Zhou, H Ailifeire, J Wu… - Journal of Clinical …, 2024 - jci.org
Maintaining protein homeostasis (proteostasis) requires precise control of protein folding
and degradation. Failure to properly respond to stresses disrupts proteostasis, which is a …

[PDF][PDF] Anticataract activity of ethanolic extract from Hippobroma longiflora (L.) G. Don leaves: Ex vivo investigation

E Imelda, K Khairan, RR Lubis, P Kemala… - Journal of Pharmacy & …, 2023 - jppres.com
Abstract Context: In Aceh, Hippobroma longiflora, known as kitolod by the locals, is believed
to possess medicinal benefits such as anticataract. Aims: To investigate the anticataract …

The Y46D Mutation Destabilizes Dense Packing of the Second Greek Key Pair of Human γC-Crystallin Causing Congenital Nuclear Cataracts

VPR Vendra, C Ostrowski, R Clark, M Dyba… - Biochemistry, 2023 - ACS Publications
The γ-crystallins are highly expressed structural lens proteins comprising four Greek key
motifs arranged in two domains. Their globular structure and short-range spatial ordering …

Cataract-causing variant Q70P damages structural stability of βB1-crystallin and increases its tendency to form insoluble aggregates

Y Zhang, L Ren, W Wu, J Liu, Q Tian, K Yao… - International Journal of …, 2023 - Elsevier
Congenital cataract is the primary cause of childhood blindness worldwide. As the
predominant structural protein, βB1-crystallin plays an important role in maintaining lens …

Impact of hydrogen peroxide on structure, stability, and aggregational properties of human γS-crystallin

VPR Vendra - Journal of Biosciences, 2023 - Springer
Cataract is the leading cause of blindness worldwide. Oxidative stress is one of the known
risk factors for age-related cataracts. The present study was designed to understand the …

Продукты окислительной модификации липидов во внутриглазной жидкости у пациентов с катарактой при хронических неинфекционных заболеваниях

МА Петренко, ЕА Бородин - Бюллетень физиологии и патологии …, 2024 - cfpd.elpub.ru
Аннотация Введение. Для выяснения роли окислительного стресса в развитии
катаракты необходимо исследование содержания продуктов окислительной …

[HTML][HTML] Anticataract activity of Hippobroma longiflora leaf extract

Abstract Context: In Aceh, Hippobroma longiflora, known as kitolodby the locals, is believed
to possess medicinal benefits such as anticataract. Aims: To investigate the anticataract …