Understanding the neurovascular unit at multiple scales: advantages and limitations of multi-photon and functional ultrasound imaging
Developing efficient brain imaging technologies by combining a high spatiotemporal
resolution and a large penetration depth is a key step for better understanding the …
resolution and a large penetration depth is a key step for better understanding the …
On the models for understanding the second harmonic generation scattering from lipid membranes and the corresponding molecular kinetics
S Chen, Y Hou, B Xu, S Chen, Q Yuan… - Colloids and Surfaces A …, 2023 - Elsevier
The kinetics of molecular transportation through lipid membranes are key information for
understanding many biophysical processes in real cells or protocells. Second harmonic …
understanding many biophysical processes in real cells or protocells. Second harmonic …
Brain white matter morphological structure correlation with its optical properties estimated from optical coherence tomography (OCT) data
A pilot post-mortem study identifies a strong correlation between the attenuation coefficient
estimated from the OCT data and some morphological features of the sample, namely the …
estimated from the OCT data and some morphological features of the sample, namely the …
Automated label‐free detection of injured neuron with deep learning by two‐photon microscopy
S Wang, B Lin, G Lin, R Lin, F Huang… - Journal of …, 2020 - Wiley Online Library
Stroke is a significant cause of morbidity and long‐term disability globally. Detection of
injured neuron is a prerequisite for defining the degree of focal ischemic brain injury, which …
injured neuron is a prerequisite for defining the degree of focal ischemic brain injury, which …
Label-free multiphoton imaging of β-amyloid plaques in Alzheimer's disease mouse models
S Wang, B Lin, G Lin, C Sun, R Lin, J Huang… - …, 2019 - spiedigitallibrary.org
β-Amyloid (Aβ) plaque, representing the progressive accumulation of the protein that mainly
consists of Aβ, is one of the prominent pathological hallmarks of Alzheimer's disease (AD) …
consists of Aβ, is one of the prominent pathological hallmarks of Alzheimer's disease (AD) …
Optical visualization of cerebral cortex by label-free multiphoton microscopy
Cortical structures in the central nervous system exhibit an ordered laminar organization.
Defined cell layers are significant to our understanding of brain structure and function. In this …
Defined cell layers are significant to our understanding of brain structure and function. In this …
Quantification of collagen organization after nerve repair
Background: Clinical outcomes after nerve injury and repair remain suboptimal. Patients
may be plagued by poor functional recovery and painful neuroma at the repair site …
may be plagued by poor functional recovery and painful neuroma at the repair site …
Label-free detection of the architectural feature of blood vessels in glioblastoma based on multiphoton microscopy
S Wang, X Sun, Z Chen, F Huang… - IEEE Journal of …, 2021 - ieeexplore.ieee.org
Glioblastoma (GBM) is a highly angiogenesis malignant tumor with a significant
heterogeneity of vascular morphology. The vascular patterns could be served as an …
heterogeneity of vascular morphology. The vascular patterns could be served as an …
Rapid, label‐free detection of intracranial germinoma using multiphoton microscopy
N Fang, Z Wu, X Wang, N Cao, Y Lin, L Li… - …, 2019 - spiedigitallibrary.org
Accurate histopathological diagnosis is essential for facilitating the optimal surgical
management of intracranial germinoma. Current intraoperative histological methods are …
management of intracranial germinoma. Current intraoperative histological methods are …
Spatial and temporal identification of cerebral infarctions based on multiphoton microscopic imaging
Ischemic stroke is a leading cause of death and permanent disability worldwide. Middle
cerebral artery occlusion (MCAO) of variable duration times could be anticipated to result in …
cerebral artery occlusion (MCAO) of variable duration times could be anticipated to result in …