[HTML][HTML] Basics of androgen synthesis and action
Androgens are essential sex steroid hormones for both sexes. Testosterone (T) is the
predominant androgen in males, while in adult females, T concentrations are about 15-fold …
predominant androgen in males, while in adult females, T concentrations are about 15-fold …
Global disorders of sex development update since 2006: perceptions, approach and care
PA Lee, A Nordenström, CP Houk, SF Ahmed… - Hormone research in …, 2016 - karger.com
The goal of this update regarding the diagnosis and care of persons with disorders of sex
development (DSDs) is to address changes in the clinical approach since the 2005 …
development (DSDs) is to address changes in the clinical approach since the 2005 …
Reactive oxygen species in male reproduction: A boon or a bane?
S Baskaran, R Finelli, A Agarwal, R Henkel - Andrologia, 2021 - Wiley Online Library
Reactive oxygen species (ROS) are free radicals derived from oxygen during normal cellular
metabolism. ROS play a crucial role in the physiological processes and signalling pathways …
metabolism. ROS play a crucial role in the physiological processes and signalling pathways …
Evolution of steroids during pregnancy: Maternal, placental and fetal synthesis
Progesterone, estrogens, androgens and glucocorticoids are involved in pregnancy from
implantation to parturition. Their biosynthesis and their metabolism result from complex …
implantation to parturition. Their biosynthesis and their metabolism result from complex …
Sex hormones and acne
Q Ju, T Tao, T Hu, AS Karadağ, S Al-Khuzaei… - Clinics in …, 2017 - Elsevier
The skin is an endocrine organ with the expression of metabolizing enzymes and hormone
receptors for diverse hormones. The sebaceous gland is the main site of hormone …
receptors for diverse hormones. The sebaceous gland is the main site of hormone …
[HTML][HTML] Antioxidant, anti-inflammatory and anti-apoptotic effects of hydro-ethanolic extract of Cyperus esculentus L.(tigernut) on lead acetate-induced testicular …
AL Udefa, EA Amama, EA Archibong… - Biomedicine & …, 2020 - Elsevier
Aim Lead acetate impairs testicular function by enhancing testicular oxidative stress and
apoptosis. Cyperus esculentus possesses antioxidants and has shown great improvement …
apoptosis. Cyperus esculentus possesses antioxidants and has shown great improvement …
[HTML][HTML] Development and function of the fetal adrenal
The adrenal cortex undergoes multiple structural and functional rearrangements to satisfy
the systemic needs for steroids during fetal life, postnatal development, and adulthood. A …
the systemic needs for steroids during fetal life, postnatal development, and adulthood. A …
Edaravone alleviates methotrexate-induced testicular injury in rats: Implications on inflammation, steroidogenesis, and Akt/p53 signaling
EHM Hassanein, WR Mohamed, RM Hussein… - International …, 2023 - Elsevier
Edaravone (ED) is a neuroprotective drug with beneficial effects against several disorders
due to its prominent antioxidant activity. However, its effect against methotrexate (MTX) …
due to its prominent antioxidant activity. However, its effect against methotrexate (MTX) …
[HTML][HTML] Clinical perspectives in congenital adrenal hyperplasia due to 3β-hydroxysteroid dehydrogenase type 2 deficiency
AM Al Alawi, A Nordenström, H Falhammar - Endocrine, 2019 - Springer
Purpose 3β-hydroxysteroid dehydrogenase type 2 deficiency (3βHSD2D) is a very rare
variant of congenital adrenal hyperplasia (CAH) causing less than 0.5% of all CAH. The aim …
variant of congenital adrenal hyperplasia (CAH) causing less than 0.5% of all CAH. The aim …
P450 Oxidoreductase deficiency: analysis of mutations and polymorphisms
Cytochrome P450 oxidoreductase (POR) is required for metabolic reactions of steroid and
drug metabolizing cytochrome P450 proteins located in endoplasmic reticulum. Mutations in …
drug metabolizing cytochrome P450 proteins located in endoplasmic reticulum. Mutations in …