The gut microbiota has a critical role in the maintenance of immune homeostasis. Alterations
in the intestinal microbiota and gut microbiota-derived metabolites have been recognized in …

The gut microbiome has emerged as a key regulator of host metabolism. Here we review the
various mechanisms through which the gut microbiome influences the energy metabolism of …

Tryptophan is catabolized by gut microorganisms resulting in a wide range of metabolites
implicated in both beneficial and adverse host effects. How gut microbial tryptophan …

Background: Accumulating evidence has shown that disorders in the gut microbiota and
derived metabolites affect the development of atherosclerotic cardiovascular disease …

Cognitive decline is one of the complications of type 2 diabetes (T2D). Intermittent fasting
(IF) is a promising dietary intervention for alleviating T2D symptoms, but its protective effect …

Objective Tryptophan can be catabolised to various metabolites through host kynurenine
and microbial indole pathways. We aimed to examine relationships of host and microbial …

Actions of symbiotic gut microbiota are in dynamic balance with the host's organism to
maintain homeostasis. Many different factors have an impact on this relationship, including …

New knowledge about the gut microbiota and its interaction with the host's metabolic
regulation has emerged during the last few decades. Several factors may affect the …

Microbial metabolites have emerged as critical components that mediate the metabolic
effects of the gut microbiota. Here, we show that indole-3-propionic acid (IPA), a tryptophan …

Overweight and obesity are associated with several cardiometabolic risk factors, including
insulin resistance, type 2 diabetes, low-grade inflammation and liver diseases. The gut …