[HTML][HTML] Nanopore sequencing technology, bioinformatics and applications
Rapid advances in nanopore technologies for sequencing single long DNA and RNA
molecules have led to substantial improvements in accuracy, read length and throughput …
molecules have led to substantial improvements in accuracy, read length and throughput …
[HTML][HTML] Next-generation sequencing technologies and their application to the study and control of bacterial infections
J Besser, HA Carleton, P Gerner-Smidt… - Clinical microbiology …, 2018 - Elsevier
Background With the efficiency and the decreasing cost of next-generation sequencing, the
technology is being rapidly introduced into clinical and public health laboratory practice …
technology is being rapidly introduced into clinical and public health laboratory practice …
Peptide sequencing based on host–guest interaction-assisted nanopore sensing
Y Zhang, Y Yi, Z Li, K Zhou, L Liu, HC Wu - Nature methods, 2024 - nature.com
Direct protein sequencing technologies with improved sensitivity and throughput are still
needed. Here, we propose an alternative method for peptide sequencing based on …
needed. Here, we propose an alternative method for peptide sequencing based on …
Three decades of nanopore sequencing
A long-held goal in sequencing has been to use a voltage-biased nanoscale pore in a
membrane to measure the passage of a linear, single-stranded (ss) DNA or RNA molecule …
membrane to measure the passage of a linear, single-stranded (ss) DNA or RNA molecule …
[HTML][HTML] Science and technology roadmap for graphene, related two-dimensional crystals, and hybrid systems
We present the science and technology roadmap for graphene, related two-dimensional
crystals, and hybrid systems, targeting an evolution in technology, that might lead to impacts …
crystals, and hybrid systems, targeting an evolution in technology, that might lead to impacts …
Overcoming ABC transporter-mediated multidrug resistance: Molecular mechanisms and novel therapeutic drug strategies
Multidrug resistance is a key determinant of cancer chemotherapy failure. One of the major
causes of multidrug resistance is the enhanced efflux of drugs by membrane ABC …
causes of multidrug resistance is the enhanced efflux of drugs by membrane ABC …
A complete bacterial genome assembled de novo using only nanopore sequencing data
We have assembled de novo the Escherichia coli K-12 MG1655 chromosome in a single 4.6-
Mb contig using only nanopore data. Our method has three stages:(i) overlaps are detected …
Mb contig using only nanopore data. Our method has three stages:(i) overlaps are detected …
FraC nanopores with adjustable diameter identify the mass of opposite-charge peptides with 44 dalton resolution
A high throughput single-molecule method for identifying peptides and sequencing proteins
based on nanopores could reduce costs and increase speeds of sequencing, allow the …
based on nanopores could reduce costs and increase speeds of sequencing, allow the …
[HTML][HTML] Assessing the performance of the oxford nanopore technologies minion
T Laver, J Harrison, PA O'neill, K Moore… - Biomolecular detection …, 2015 - Elsevier
Abstract The Oxford Nanopore Technologies (ONT) MinION is a new sequencing technology
that potentially offers read lengths of tens of kilobases (kb) limited only by the length of DNA …
that potentially offers read lengths of tens of kilobases (kb) limited only by the length of DNA …
Nanopore-based fourth-generation DNA sequencing technology
Nanopore-based sequencers, as the fourth-generation DNA sequencing technology, have
the potential to quickly and reliably sequence the entire human genome for less than 1000 …
the potential to quickly and reliably sequence the entire human genome for less than 1000 …