Recent advances in catalytic hairpin assembly signal amplification-based sensing strategies for microRNA detection

Y Wu, C Fu, W Shi, J Chen - Talanta, 2021 - Elsevier
Accumulative evidences have indicated that abnormal expression of microRNAs (miRNAs)
is closely associated with many health disorders, making them be regarded as …

Recent advances in DNA walker machines and their applications coupled with signal amplification strategies: A critical review

M Xu, D Tang - Analytica Chimica Acta, 2021 - Elsevier
DNA walkers, a type of dynamic nanomachines, have become the subject of burgeoning
research in the field of biology. These walkers are powered by driving forces based on …

Flexible self-powered sensing system based on novel DNA circuit strategy and graphdiyne for thalassemia gene by rapid naked-eye tracking and open-circuit voltage

D Tang, J Shi, Y Wu, H Luo, J Yan, KJ Huang… - Analytical …, 2023 - ACS Publications
Based on the controllable instantaneous self-assembly ability of long-chain branched DNA
nanostructures and the synergistic effect between nucleic acid amplification without …

A novel ratiometric electrochemical biosensor using only one signal tag for highly reliable and ultrasensitive detection of miRNA-21

L Kong, H Li, X Zhang, Y Zhuo, Y Chai… - Analytical …, 2022 - ACS Publications
Herein, a novel ratiometric electrochemical biosensor with methylene blue (MB) as the only
one signal tag was proposed for highly reliable and ultrasensitive detection of microRNA-21 …

A CRISPR/Cas12a-mediated dual-mode electrochemical biosensor for polymerase chain reaction-free detection of genetically modified soybean

H Ge, X Wang, J Xu, H Lin, H Zhou, T Hao… - Analytical …, 2021 - ACS Publications
A clustered regularly interspaced short palindromic repeats (CRISPR)/Cas12a-mediated
dual-mode electrochemical biosensor without polymerase chain reaction (PCR) …

Rapid electrochemical biosensor for sensitive profiling of exosomal microRNA based on multifunctional DNA tetrahedron assisted catalytic hairpin assembly

Y Zhang, X Zhang, B Situ, Y Wu, S Luo, L Zheng… - Biosensors and …, 2021 - Elsevier
Profiling of exosomal microRNA (exo-miRNA) is very important for cancer diagnosis and
treatment. However, rapid and sensitive determination the trace of exo-miRNA in clinical …

Rational engineering the DNA tetrahedrons of dual wavelength ratiometric electrochemiluminescence biosensor for high efficient detection of SARS-CoV-2 RdRp …

Z Fan, B Yao, Y Ding, D Xu, J Zhao, K Zhang - Chemical Engineering …, 2022 - Elsevier
Fast and effective detection of epidemics is the key to preventing the spread of diseases. In
this work, we constructed a dual-wavelength ratiometric electrochemiluminescence (ECL) …

Signal amplification strategies in electrochemiluminescence biosensors

D Han, K Yang, S Sun, J Wen - Chemical Engineering Journal, 2023 - Elsevier
Electrochemiluminescence (ECL) has attracted widespread attention in various analytical
fields, due to its remarkable potential, such as high sensitivity, wide dynamic range and …

Zinc porphyrin/MXene hybrids with phosphate-induced stimuli-responsive behavior for dual-mode fluorescent/electrochemiluminescent ratiometric biosensing

H Sun, J Guan, H Chai, K Yu, L Qu, X Zhang… - Biosensors and …, 2024 - Elsevier
Highly sensitive ratiometric biosensors have attracted much attention in biomarker detection,
but most rely on single-mode signals, which can affect accuracy. The development of new …

Self-powered DNAzyme walker enables dual-mode biosensor construction for electrochemiluminescence and electrochemical detection of microRNA

S Du, B Xie, H Gao, J Zhang, H Fu, F Liao… - Analytical …, 2023 - ACS Publications
Herein, an electrochemiluminescence (ECL) and electrochemical (EC) dual-mode
biosensor platform with a self-powered DNAzyme walking machine was established for …