Malignant peripheral nerve sheath tumors—a comprehensive review of pathophysiology, diagnosis, and multidisciplinary management

SWE Knight, TE Knight, T Santiago, AJ Murphy… - Children, 2022 - mdpi.com
Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas
(STS) with nerve sheath differentiation and a tendency to metastasize. Although occurring at …

Malignant peripheral nerve sheath tumors: latest concepts in disease pathogenesis and clinical management

C Yao, H Zhou, Y Dong, A Alhaskawi… - Cancers, 2023 - mdpi.com
Simple Summary Malignant peripheral nerve sheath tumor (MPNST) is a soft tissue sarcoma
with limited therapeutic interventions and a poor prognosis. This review summarized the …

[HTML][HTML] A nationwide cohort study on treatment and survival in patients with malignant peripheral nerve sheath tumours

E Martin, JH Coert, UE Flucke, WBM Slooff… - European Journal of …, 2020 - Elsevier
Background Despite curative intents of treatment in localized malignant peripheral nerve
sheath tumours (MPNSTs), prognosis remains poor. This study investigated survival and …

Prognosis and risk factors for malignant peripheral nerve sheath tumor: a systematic review and meta-analysis

Z Cai, X Tang, H Liang, R Yang, T Yan… - World Journal of Surgical …, 2020 - Springer
Background No available meta-analysis was printed to systematically introduce the MPNST
clinic outcome and risk factors based on largely pooled data. This systematic review and …

Targeting the peripheral neural-tumour microenvironment for cancer therapy

D Yaniv, B Mattson, S Talbot, FO Gleber-Netto… - Nature Reviews Drug …, 2024 - nature.com
As the field of cancer neuroscience expands, the strategic targeting of interactions between
neurons, cancer cells and other elements in the tumour microenvironment represents a …

Non-squamous laryngeal cancer

SD MacNeil - Otolaryngologic Clinics of North America, 2023 - oto.theclinics.com
Non-squamous cell carcinoma (SCC) of the larynx represents approximately 5% of
laryngeal malignancies. 1 These malignancies originate from minor salivary glands, bone …

Management of central and peripheral nervous system tumors in patients with neurofibromatosis

R Brown - Current Oncology Reports, 2023 - Springer
Abstract Neurofibromatosis type I (NF1), neurofibromatosis type 2 (NF2), and
schwannomatosis represent a diverse group of genetic tumor predisposition syndromes with …

Neurofibromatosis‐associated malignant peripheral nerve sheath tumors in children have a worse prognosis: A nationwide cohort study

E Martin, JH Coert, UE Flucke, WBM Slooff… - Pediatric blood & …, 2020 - Wiley Online Library
Background Malignant peripheral nerve sheath tumors (MPNST) are rare and aggressive
non‐rhabdomyoblastic soft‐tissue sarcomas (NRSTS) in children. This study set out to …

Update on immunohistochemistry in bone and soft tissue tumors: Cost-effectively replacing molecular testing with immunohistochemistry

C Wakefield, JL Hornick - Human Pathology, 2024 - Elsevier
Soft tissue tumors form part of a challenging domain in diagnostic pathology owing to their
comparative rarity, astonishing histologic diversity, and overlap between entities. Many of …

Survival outcomes of malignant peripheral nerve sheath tumors (MPNSTs) with and without neurofibromatosis type I (NF1): a meta-analysis

Z Lim, TY Gu, BC Tai, ME Puhaindran - World Journal of Surgical …, 2024 - Springer
Introduction Malignant peripheral nerve sheath tumors (MPNSTs) are malignancies that
demonstrate nerve sheath differentiation in the peripheral nervous system. They can occur …