Modulating the gut microbiome and its influence on human health is the subject of intense
research. The gut microbiota could be associated not only with gastroenterological diseases …

Depression is a heterogeneous mental disorder characterized by feelings of sadness and
loss of interest that render the subject unable to handle basic daily activities such as …

Evidences have shown that both LRFN5 and OLFM4 can regulate neural development and
synaptic function. Recent genome-wide association studies on major depressive disorder …

The cell-free DNA (cfDNA) levels are known to increase in biological fluids in various
pathological conditions. However, the data on circulating cfDNA in severe psychiatric …

Aim Schizophrenia onset in the developmental age has a strong neurodevelopmental
burden and is associated with a poorer prognosis. The approach to diagnosis is still based …

There is a paucity of biomarkers for the prediction of treatment response in schizophrenia. In
this study, we aimed to investigate whether diminished antipsychotic treatment response in …

Background Gut microbiota plays a pivotal role in the gut-brain axis and can influence
neurodevelopment and mental health outcomes. This review summarizes the current …

Introduction Macrophages or T-lymphocytes triggered inflammation and, consequently,
activated glial cells may contribute to neuroinflammation and neurotransmitter dysfunction in …

2. Methods The local ethics committee of Chongqing Medical University approved this study.
Each participant gave their written informed permission before collecting blood samples …

Objective Immune system dysregulation is hypothesised to be central to the
aetiopathogenesis of schizophrenia; however, the role of sterile inflammation remains …