Levoglucosenone: bio-based platform for drug discovery

JE Camp, BW Greatrex - Frontiers in Chemistry, 2022 - frontiersin.org
Levoglucosone (LGO) is a bio-privileged molecule that can be produced on scale from
waste biomass. This chiral building block has been converted via well-established chemical …

Levoglucosenone and its new applications: valorization of cellulose residues

MB Comba, Y Tsai, AM Sarotti… - European Journal of …, 2018 - Wiley Online Library
The need to find sustainable alternatives to reduce the dependence on fossil sources has
led to significant research efforts on the conversion of biomass into platform chemicals …

Application of 1, 3‐Dipolar Reactions between Azomethine Ylides and Alkenes to the Synthesis of Catalysts and Biologically Active Compounds

I Arrastia, A Arrieta, FP Cossío - European Journal of Organic …, 2018 - Wiley Online Library
The (3+ 2) cycloaddition between azomethine ylides and alkenes is an efficient, convergent
and stereocontrolled method for the synthesis of unnatural pyrrolidine and proline scaffolds …

Enantioselective dearomative [3+ 2] cycloadditions of indoles with azomethine ylides derived from alanine imino esters

AL Gerten, LM Stanley - Organic Chemistry Frontiers, 2016 - pubs.rsc.org
Catalytic, enantioselective [3+ 2] cycloadditions of azomethine ylides derived from alanine
imino esters with 3-nitroindoles are reported. The dearomative cycloaddition reactions occur …

Regio-and stereoselective synthesis of spiropyrrolizidines and piperazines through azomethine ylide cycloaddition reaction

S Haddad, S Boudriga, F Porzio… - The Journal of …, 2015 - ACS Publications
A series of original spiropyrrolizidine derivatives has been prepared by a one-pot three-
component [3+ 2] cycloaddition reaction of (E)-3-arylidene-1-phenyl-pyrrolidine-2, 5-diones …

Regio-and stereoselective synthesis of spirooxindole 1′-nitro pyrrolizidines with five concurrent stereocenters under aqueous medium and their bioprospection using …

CEP Galvis, VV Kouznetsov - Organic & Biomolecular Chemistry, 2013 - pubs.rsc.org
A highly regio-and stereoselective method has been developed and expanded for the
synthesis of a 20-membered library of spirooxindole 1′-nitro pyrrolizidines via 1, 3-dipolar …

Valorization of waste: Sustainable organocatalysts from renewable resources

S Meninno - ChemSusChem, 2020 - Wiley Online Library
One of the greatest challenges facing our society is to reconcile our need to develop efficient
and sophisticated chemical processes with the limited resources of our planet and its …

Determination of the relative configuration of terminal and spiroepoxides by computational methods. Advantages of the inclusion of unscaled data

MM Zanardi, AG Suárez, AM Sarotti - The Journal of organic …, 2017 - ACS Publications
The assignment of the relative configuration of spiroepoxides or related quaternary carbon-
containing oxiranes can be troublesome and difficult to achieve. The use of GIAO NMR shift …

Thiazolidine-2, 4-dione framework containing spiropyrrolidine-oxindole and 1, 2, 3-triazole scaffold: synthesis, in vitro α-amylase inhibition and in silico studies

M Duhan, R Singh, M Devi, J Sindhu, P Kumar… - New Journal of …, 2023 - pubs.rsc.org
In an attempt to develop novel α-amylase inhibitors, a series of 2, 4-thiazolidinedione fused
spiropyrrolidine-oxindole and 1, 2, 3-triazole scaffolds were designed, synthesized via a …

Organocatalysts Derived from Unnatural α‐Amino Acids: Scope and Applications

M Agirre, A Arrieta, I Arrastia… - Chemistry–An Asian …, 2019 - Wiley Online Library
The organocatalytic properties of unnatural α‐amino acids are reviewed. Post‐translational
derivatives of natural α‐amino acids include 4‐hydroxy‐l‐proline and 4‐amino‐l‐proline …