[HTML][HTML] Comprehensive literature review of hyperpolarized carbon-13 MRI: the road to clinical application

M Vaeggemose, R F. Schulte, C Laustsen - Metabolites, 2021 - mdpi.com
This review provides a comprehensive assessment of the development of hyperpolarized
(HP) carbon-13 metabolic MRI from the early days to the present with a focus on clinical …

Development of methods and feasibility of using hyperpolarized carbon‐13 imaging data for evaluating brain metabolism in patient studies

I Park, PEZ Larson, JW Gordon… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose Hyperpolarized carbon‐13 (13C) metabolic imaging is a noninvasive imaging
modality for evaluating real‐time metabolism. The purpose of this study was to develop and …

Fast imaging for hyperpolarized MR metabolic imaging

JW Gordon, HY Chen, N Dwork, S Tang… - Journal of Magnetic …, 2021 - Wiley Online Library
MRI with hyperpolarized carbon‐13 agents has created a new type of noninvasive, in vivo
metabolic imaging that can be applied in cell, animal, and human studies. The use of 13C …

Translation of Carbon‐13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients

JW Gordon, HY Chen, A Autry, I Park… - Magnetic resonance …, 2019 - Wiley Online Library
Purpose To develop and translate a metabolite‐specific imaging sequence using a
symmetric echo planar readout for clinical hyperpolarized (HP) Carbon‐13 (13C) …

[HTML][HTML] Hyperpolarized [2–13C] pyruvate MR molecular imaging with whole brain coverage

BT Chung, Y Kim, JW Gordon, HY Chen, AW Autry… - NeuroImage, 2023 - Elsevier
Abstract Hyperpolarized (HP) 13 C Magnetic Resonance Imaging (MRI) was applied for the
first time to image and quantify the uptake and metabolism of [2–13 C] pyruvate in the …

Coil combination methods for multi-channel hyperpolarized 13C imaging data from human studies

Z Zhu, X Zhu, MA Ohliger, S Tang, P Cao… - Journal of Magnetic …, 2019 - Elsevier
Effective coil combination methods for human hyperpolarized 13 C spectroscopy multi-
channel data had been relatively unexplored. This study implemented and tested several …

The use of hyperpolarized carbon-13 magnetic resonance for molecular imaging

S Siddiqui, S Kadlecek, M Pourfathi, Y Xin… - Advanced drug delivery …, 2017 - Elsevier
Until recently, molecular imaging using magnetic resonance (MR) has been limited by the
modality's low sensitivity, especially with non-proton nuclei. The advent of hyperpolarized …

RF coil design for accurate parallel imaging on 13C MRSI using 23Na sensitivity profiles

JD Sanchez‐Heredia, RB Olin, JT Grist… - Magnetic resonance …, 2022 - Wiley Online Library
Purpose To develop a coil‐based method to obtain accurate sensitivity profiles in 13C MRI
at 3T from the endogenous 23Na. An eight‐channel array is designed for 13C MR …

Dynamic 13C MR spectroscopy as an alternative to imaging for assessing cerebral metabolism using hyperpolarized pyruvate in humans

J Ma, MC Pinho, CE Harrison, J Chen… - Magnetic resonance …, 2022 - Wiley Online Library
Purpose This study is to investigate time‐resolved 13C MR spectroscopy (MRS) as an
alternative to imaging for assessing pyruvate metabolism using hyperpolarized (HP)[1‐13C] …

Coil profile estimation strategies for parallel imaging with hyperpolarized 13C MRI

RB Hansen, JD Sánchez‐Heredia… - Magnetic resonance …, 2019 - Wiley Online Library
Purpose To investigate auto‐and pre‐calibration coil profile estimation for parallel imaging
reconstruction of hyperpolarized 13C MRI volumetric data. Methods Parallel imaging …