Mechanisms and management of thyroid disease and atrial fibrillation: impact of atrial electrical remodeling and cardiac fibrosis

A Takawale, M Aguilar, Y Bouchrit, R Hiram - Cells, 2022 - mdpi.com
Atrial fibrillation (AF) is the most common cardiac arrhythmia associated with increased
cardiovascular morbidity and mortality. The pathophysiology of AF is characterized by …

Graves' disease as a driver of depression: a mechanistic insight

Y Song, X Wang, W Ma, Y Yang, S Yan, J Sun… - Frontiers in …, 2023 - frontiersin.org
Graves' disease (GD) is characterized by diffuse enlargement and overactivity of the thyroid
gland, which may be accompanied by other physical symptoms. Among them, depression …

Minor perturbations of thyroid homeostasis and major cardiovascular endpoints—Physiological mechanisms and clinical evidence

P Müller, MKS Leow, JW Dietrich - Frontiers in Cardiovascular …, 2022 - frontiersin.org
It is well established that thyroid dysfunction is linked to an increased risk of cardiovascular
morbidity and mortality. The pleiotropic action of thyroid hormones strongly impacts the …

Thyroid hormone and thyroid hormone nuclear receptors: History and present state of art

J Brtko - Endocrine Regulations, 2021 - sciendo.com
The present review traces the road leading to discovery of L-thyroxine, thyroid hormone (3,
5, 3-triiodo-L-thyronine, T3) and its cognate nuclear receptors. Thyroid hormone is a …

Levothyroxine treatment and the risk of cardiac arrhythmias–focus on the patient submitted to thyroid surgery

Z Gluvic, M Obradovic, AJ Stewart, M Essack… - Frontiers in …, 2021 - frontiersin.org
Levothyroxine (LT4) is used to treat frequently encountered endocrinopathies such as
thyroid diseases. It is regularly used in clinical (overt) hypothyroidism cases and subclinical …

Association of thyroid dysfunction in individuals≥ 65 years of age with subclinical cardiac abnormalities

E Barasch, J Gottdiener, P Buzkova… - The Journal of …, 2024 - academic.oup.com
Context The relationship between thyroid dysfunction and measures of myocardial disease
in older individuals remains to be defined. Objective To evaluate the impact of thyroid …

The bidirectional relationship of thyroid disease and atrial fibrillation: Established knowledge and future considerations

A Bekiaridou, A Kartas, DV Moysidis… - Reviews in Endocrine …, 2022 - Springer
Atrial fibrillation (AF) tends to occur frequently in patients with thyroid disease, primarily
hyperthyroidism. In hyperthyroidism, increased levels of thyroid hormones, via intra-and …

Hypertension Induces Pro-arrhythmic cardiac connexome disorders: protective effects of treatment

M Sykora, K Andelova, B Szeiffova Bacova… - Biomolecules, 2023 - mdpi.com
Prolonged population aging and unhealthy lifestyles contribute to the progressive
prevalence of arterial hypertension. This is accompanied by low-grade inflammation and …

Higher risk of incident hyperthyroidism in patients with atrial fibrillation

PS Huang, JF Cheng, JJ Chen, YC Wang… - The Journal of …, 2024 - academic.oup.com
Background Atrial fibrillation (AF) has been linked to increased hyperthyroidism risk, but
contributing factors are unclear. Objective We aimed to investigate whether AF could predict …

[HTML][HTML] Benefit and Preference of Propranolol Over Metoprolol in Thyrotoxicosis-Induced Atrial Fibrillation: a case report and review of literature

MF Obi, V Namireddy, Y Garg, M Sharma - Cureus, 2023 - ncbi.nlm.nih.gov
Atrial fibrillation is a common manifestation seen in patients with hyperthyroidism and thyroid
storm. The presence of excess thyroid hormone (TH) alters adrenergic receptors in the heart …