Chromatin crosstalk in development and disease: lessons from REST
L Ooi, IC Wood - Nature Reviews Genetics, 2007 - nature.com
Protein complexes that contain chromatin-modifying enzymes have an important role in
regulating gene expression. Recent studies have shown that a single transcription factor, the …
regulating gene expression. Recent studies have shown that a single transcription factor, the …
Cellular mechanisms for the biogenesis and transport of synaptic and dense-core vesicles
MC Gondré-Lewis, JJ Park, YP Loh - … review of cell and molecular biology, 2012 - Elsevier
The release of intercellular messengers from synaptic (SVs) and dense-core vesicles
(DCVs) constitutes the primary mechanism for communication between neighboring or …
(DCVs) constitutes the primary mechanism for communication between neighboring or …
A Mutation in the Srrm4 Gene Causes Alternative Splicing Defects and Deafness in the Bronx Waltzer Mouse
Y Nakano, I Jahan, G Bonde, X Sun, MS Hildebrand… - 2012 - journals.plos.org
Sensory hair cells are essential for hearing and balance. Their development from epithelial
precursors has been extensively characterized with respect to transcriptional regulation, but …
precursors has been extensively characterized with respect to transcriptional regulation, but …
Differential expression of the regulated catecholamine secretory pathway in different hereditary forms of pheochromocytoma
G Eisenhofer, TT Huynh, A Elkahloun… - American Journal …, 2008 - journals.physiology.org
Pheochromocytomas in patients with von Hippel-Lindau (VHL) syndrome and multiple
endocrine neoplasia type 2 (MEN 2) differ in the types and amounts of catecholamines …
endocrine neoplasia type 2 (MEN 2) differ in the types and amounts of catecholamines …
[HTML][HTML] REST/NRSF governs the expression of dense-core vesicle gliosecretion in astrocytes
I Prada, J Marchaland, P Podini, L Magrassi… - The Journal of cell …, 2011 - ncbi.nlm.nih.gov
Astrocytes are the brain nonnerve cells that are competent for gliosecretion, ie, for
expression and regulated exocytosis of clear and dense-core vesicles (DCVs). We …
expression and regulated exocytosis of clear and dense-core vesicles (DCVs). We …
The deubiquitylase USP15 stabilizes newly synthesized REST and rescues its expression at mitotic exit
Reversible ubiquitylation of proteins contributes to their integrity, abundance and activity.
The RE1-silencing transcription factor (REST) plays key physiological roles and is …
The RE1-silencing transcription factor (REST) plays key physiological roles and is …
SCG3 transcript in peripheral blood is a prognostic biomarker for REST-deficient small cell lung cancer
AC Moss, GM Jacobson, LE Walker, NW Blake… - Clinical Cancer …, 2009 - AACR
Purpose: Specific markers of circulating tumor cells may be informative in managing lung
cancer. Because the RE-1 silencing transcription factor (REST/NRSF) is a transcriptional …
cancer. Because the RE-1 silencing transcription factor (REST/NRSF) is a transcriptional …
Regulation of gene expression in the nervous system
The nervous system contains a multitude of cell types which are specified during
development by cascades of transcription factors acting combinatorially. Some of these …
development by cascades of transcription factors acting combinatorially. Some of these …
Pro-hormone secretogranin II regulates dense core secretory granule biogenesis in catecholaminergic cells
M Courel, A Soler-Jover, JL Rodriguez-Flores… - Journal of Biological …, 2010 - ASBMB
Processes underlying the formation of dense core secretory granules (DCGs) of
neuroendocrine cells are poorly understood. Here, we present evidence that DCG …
neuroendocrine cells are poorly understood. Here, we present evidence that DCG …
Epigenetic modification in neuropathic pain
H Ueda, H Uchida - Current pharmaceutical design, 2015 - ingentaconnect.com
Neuropathic pain is characterized by complicated combination of positive (eg, hyperalgesia
and allodynia) and negative (eg, hypoesthesia and hypoalgesia) symptoms, and is often …
and allodynia) and negative (eg, hypoesthesia and hypoalgesia) symptoms, and is often …