Hypoxia, a deficiency in the levels of oxygen, is a common feature of most solid tumors and
induces many characteristics of cancer. Hypoxia is associated with metastases and strong …

C–F bond formation is an important research topic in organic synthesis because of the wide
use of organofluorine compounds in various areas including pharmaceuticals, agricultural …

Background Neuroinflammation plays a significant role in the progression of frontotemporal
dementia (FTD). However, the association between peripheral inflammatory factors and …

The translocator protein (TSPO) is an interesting biological target for molecular imaging and
therapy because the overexpression of TSPO is associated with microglial activation caused …

Mitochondria dysfunctions are typical hallmarks of cardiac disorders (CDs). The multiple
tasks of this energy-producing organelle are well documented, but its pathophysiologic …

Parkinson's disease (PD) is a widespread progressive neurodegenerative disease. Clinical
diagnosis approaches are insufficient to provide an early and accurate diagnosis before a …

Positron emission tomography (PET) is a noninvasive molecular imaging method
extensively applied in the detection and treatment of various diseases. Hypoxia is a common …

Ocular complications of diabetes mellitus (DM) are the leading cause of vision loss. Ocular
inflammation often occurs in the early stage of DM; however, there are no proven …

Inflammation induced by activated macrophages within vulnerable atherosclerotic plaques
(VAPs) constitutes a significant risk factor for plaque rupture. Translocator protein (TSPO) is …

Amino acid transporters are upregulated in many cancer cells, and system L amino acid
transporters (LAT1–4), in particular, LAT1, which preferentially transports large, neutral, and …