Clusterin/Apolipoprotein J (ApoJ) is a heterodimeric highly conserved secreted glycoprotein
being expressed in a wide variety of tissues and found in all human fluids. Despite being …

Hsp27 and clusterin (CLU are stress-activated small heat shock proteins that are up-
regulated in many cancers where they play important roles in stress-induced protein …

Nuclear clusterin (nCLU) is an ionizing radiation (IR)-inducible protein that binds Ku70, and
triggers apoptosis when overexpressed in MCF-7 cells. We demonstrate that endogenous …

Introduction In order to gain a better understanding of the molecular processes that underlie
apoptosis and tissue regression in mammary gland, we undertook a large-scale analysis of …

The treatment of metastatic castrate-resistant prostate cancer has been historically
challenging, with few therapeutic successes. Docetaxel was the first cytotoxic therapy …

Introduction: Clusterin (CLU) is a stress-activated, ATP-independent molecular chaperone,
normally secreted from cells, that is up-regulated in Alzheimer disease and in many cancers …

Abstract Clusterin/Apolipoprotein J (CLU) is a heterodimeric ubiquitously expressed
secreted glycoprotein that is implicated in several physiological processes and is …

The androgen receptor (AR) is a transcription factor that has a pivotal role in the occurrence
and progression of prostate cancer. The AR is activated by androgens that bind to its ligand …

TGF-β promotes epithelial–mesenchymal transition (EMT) and induces clusterin (CLU)
expression, linking these genes to cancer metastasis. CLU is a pleiotropic molecular …

Abstract Di (n-butyl) phthalate (DBP) has antiandrogenic-like effects on the developing
reproductive tract in the male rat and produces regions of interstitial cell hyperplasia and …