Although the potential for genomics to contribute to clinical care has long been anticipated,
the pace of defining the risks and benefits of incorporating genomic findings into medical …

The central theme of personalized medicine is the premise that an individual's unique
physiologic characteristics play a significant role in both disease vulnerability and in …

The objective of this study was to evaluate the effect of pharmacogenetics-guided treatment
on patients diagnosed with depression and/or anxiety, in a diverse set of clinical settings, as …

Objectives: Biomarkers are defined as anatomical, biochemical or physiological traits that
are specific to certain disorders or syndromes. The objective of this paper is to summarise …

Serotonin syndrome is a potentially fatal and largely avoidable adverse drug reaction
caused by serotonergic drugs. The steady increase in use of such drugs means all doctors …

The accrual and analysis of genomic sequencing data have identified specific genetic
variants that are associated with major depressive disorder. Moreover, substantial …

A number of candidate gene studies focused on major depression (MD) and antidepressant
(AD) efficacy have been carried out, but results mainly remain inconclusive. We performed a …

Anxiety-related psychiatric disorders represent one of the largest health burdens worldwide.
Single nucleotide polymorphisms of the FK506 binding protein 51 (FKBP51) gene have …

With recent studies using genetic, epigenetic, and other molecular and neurochemical
approaches, a new era has begun in understanding pathophysiology of suicide. Emerging …

For over a decade, the European Group for the Study of Resistant Depression (GSRD) has
examined single nucleotide polymorphisms (SNP) and clinical parameters in regard to …