Chemical synapses are heterogeneous junctions formed between neurons that are
specialized for the conversion of electrical impulses into the exocytotic release of …

At each of the brain's vast number of synapses, the presynaptic nerve terminal, synaptic cleft,
and postsynaptic specialization form a transcellular unit to enable efficient transmission of …

Presynaptic Ca V 2 channels are essential for Ca 2+-triggered exocytosis. In addition, there
are two competing models for their roles in synapse structure. First, Ca 2+ channels or Ca 2+ …

Calcium influx through voltage-gated Ca (CaV) channels is the first step in synaptic
transmission. This review concerns CaV channels at ribbon synapses in primary sense …

Voltage-gated calcium (Ca V) channels are associated with β and α 2 δ auxiliary subunits.
This review will concentrate on the function of the α 2 δ protein family, which has four …

Retinal degenerations are a heterogeneous group of diseases characterized by death of
photoreceptors and progressive loss of vision. Retinal degenerations are a major cause of …

In this review, we summarize studies investigating the types and distribution of voltage-and
calcium-gated ion channels in the different classes of retinal neurons: rods, cones …

Light-evoked voltage responses of rod and cone photoreceptor cells in the vertebrate retina
must be converted to a train of synaptic vesicle release events for transmission to …

Synapse formation within the retinal circuit ensures that distinct neuronal types can
communicate efficiently to process visual signals. Synapses thus form the core of the visual …

Abstract α 2 δ proteins are membrane-anchored extracellular glycoproteins which are
abundantly expressed in the brain and the peripheral nervous system. They serve as …