Perinatal hypoxia-ischemia remains the primary cause of acute neonatal brain injury,
leading to a high mortality rate and long-term neurological deficits, such as behavioral …

Introduction: Hypoxic ischemic encephalopathy (HIE) is the most important reason for
morbidity and mortality in term-born infants. Understanding pathophysiology of the brain …

Importance The ability to predict neurodevelopmental impairment (NDI) for infants
diagnosed with hypoxic ischemic encephalopathy (HIE) is important for parental guidance …

Objectives To evaluate plasma brain specific proteins and cytokines as biomarkers of brain
injury in newborns with hypoxic-ischemic encephalopathy (HIE) and, secondarily, to assess …

Background Neonatal stroke is a devastating insult that can lead to life-long impairments. In
response to hypoxic–ischaemic injury, there is loss of neurons and glia as well as a …

Neonatologists resuscitate asphyxiated neonates by every available means, including
positive ventilation, oxygen therapy, and drugs. Asphyxiated neonates sometimes present …

The widespread introduction of therapeutic hypothermia as a standard of care in hypoxic–
ischemic encephalopathy (HIE) has brought increasing pressure on clinicians to make an …

Identification of infants! 36 weeks' gestation with perinatal hypoxia-ischemia or asphyxia has
allowed investigation of potential neuroprotective treatments. Therapeutic hypothermia is the …

Background Neonatal hypoxic-ischemic (HI) brain injury is a leading cause of acute mortality
and chronic disability in newborns. Our previous studies demonstrated that HI insult …

Perinatal hypoxic‐ischemic encephalopathy (HIE) is a leading cause of neonatal death and
neurological disability. Oxidative stress and neuroinflammation are typical pathogenic …