The fertility and survival of an individual rely on the ability of the periphery to promptly,
effectively, and reproducibly communicate with brain neural networks that control …

Chemokines–chemotactic cytokines–are small secreted proteins that attract and activate
immune and non-immune cells in vitro and in vivo. It has been suggested that chemokines …

Most genome-wide association studies (GWAS) of major depression (MD) have been
conducted in samples of European ancestry. Here we report a multi-ancestry GWAS of MD …

Animals use current, past, and projected future states of the organism and the world in a
finely tuned system to control ingestion. They must not only deal effectively with current …

The melanin-concentrating hormone (MCH) is a 19 aminoacid peptide found in mammals
predominantly in neurons located in the lateral hypothalamus and incerto-hypothalamic …

More than 20 years ago, melanin-concentrating hormone (MCH) and its peptide family
members–neuropeptide EI (NEI) and neuropeptide GE (NGE)–were described in various …

Dioxins are ubiquitous environmental contaminants that have attracted toxicological interest
not only for the potential risk they pose to human health but also because of their unique …

Extensive studies in rodents with melanin-concentrating hormone (MCH) have
demonstrated that the neuropeptide hormone is a potent orexigen. Acutely, MCH causes an …

Physical exercise is considered beneficial in the treatment of depression, but the underlying
mechanism is not clearly understood. In the present study, we investigated the mechanism …

Accumulating evidence highlights chemokines as key mediators of the bidirectional
crosstalk between neurons and glial cells aimed at preserving brain functioning. The …