Exposure to the external environment may lead to instability and dysfunction of the skin,
resulting in refractory wound, skin aging, pigmented dermatosis, hair loss, some immune …

Juvenile systemic lupus erythematosus (JSLE) is characterised by onset before 18 years of
age and more severe disease phenotype, increased morbidity and mortality compared to …

Objective The aim of this study was to characterize childhood-onset systemic lupus
erythematosus (SLE) in two large cohorts from Turkey and the United States. Methods …

Objectives We determined the temporal association between clinical and serological
disease manifestations and development of cutaneous small vessel vasculitis in a large …

Background Age at disease onset may modulate systemic lupus erythematosus (SLE), but
its relation to cutaneous/extracutaneous manifestation remains understudied. Objective To …

Objectives Ischemic cerebrovascular disease (ICVD) is one of the most common and severe
complications in systemic lupus erythematosus (SLE). We aim to explore the risk factors for …

Slit2 glycoprotein has been described to regulate the inflammatory response and be
involved in autoimmune diseases. Here, we investigated the expression of Slit2 and its …

Regenerative medicine focuses on the use of biological methods to repair or replace tissue
or organ function that has been lost due to aging, disease, or damage. The use of …

Background Discoid lupus erythematosus (DLE) is a most well‐known clinical variation of
chronic cutaneous lupus erythematosus inside the spectrum of lupus erythematosus (LE) …

Cutaneous involvement occurs in 72%-85% of cases of systemic lupus erythematosus and
may be the first clinical sign in up to 25% of cases. 1 Recognizing these cutaneous …