[HTML][HTML] Reactivation of p53 gene by MDM2 inhibitors: A novel therapy for cancer treatment

A Gupta, K Shah, MJ Oza, T Behl - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Cancer is an uncontrolled and abnormal growth of cells in the body. Gene that guards the
cell cycle and function as tumor suppressor is p53 (also called as the guardian of the …

Oral squamous cell carcinoma: overview of current understanding of aetiopathogenesis and clinical implications

C Scully, JV Bagan - Oral diseases, 2009 - Wiley Online Library
MEDLINE contains well over 14 000 papers revealed by a search using keywords 'oral
squamous cell cancer'or 'oral squamous cell carcinoma', over 27 000 using 'oral …

[HTML][HTML] Incidence and mortality of female breast cancer in the Asia-Pacific region

DR Youlden, SM Cramb, CH Yip… - Cancer biology & …, 2014 - ncbi.nlm.nih.gov
Objective To provide an overview of the incidence and mortality of female breast cancer for
countries in the Asia-Pacific region. Methods Statistical information about breast cancer was …

Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: a representative population prospective …

MS Lee, CC Hsu, ML Wahlqvist, HN Tsai, YH Chang… - BMC cancer, 2011 - Springer
Background Metformin protection against cancer risk in Orientals is uncertain. We examined
the possible metformin effect on total, esophageal, gastric, colorectal (CRC), hepatocellular …

Gene-disease network analysis reveals functional modules in mendelian, complex and environmental diseases

A Bauer-Mehren, M Bundschus, M Rautschka… - PloS one, 2011 - journals.plos.org
Background Scientists have been trying to understand the molecular mechanisms of
diseases to design preventive and therapeutic strategies for a long time. For some diseases …

Attributable fraction of tobacco smoking on cancer using population-based nationwide cancer incidence and mortality data in Korea

S Park, SH Jee, HR Shin, EH Park, A Shin, KW Jung… - BMC cancer, 2014 - Springer
Background Smoking is by far the most important cause of cancer that can be modified at the
individual level. Cancer incidence and mortality rates in Korea are the highest among all …

Air pollution and non-respiratory health hazards for children

R Kelishadi, P Poursafa - Archives of Medical Science, 2010 - termedia.pl
Air pollution is a global health issue with serious public health implications, particularly for
children. Usually respiratory effects of air pollutants are considered, but this review …

Design, synthesis, analysis, evaluation of cytotoxicity against MCF-7 breast cancer cells, 3D QSAR studies and EGFR, HER2 inhibition studies on Novel Biginelli 1, 4 …

NL Naishima, S Faizan, RM Raju, ASVL Sruthi… - Journal of Molecular …, 2023 - Elsevier
Dihydropyrimidines are usually synthesized from Biginelli reaction which are well known for
their anti-cancer activity. A series of novel Biginelli-1, 4-dihydropyrimidines are rationally …

Prostate cancer in East Asia: evolving trend over the last decade

Y Zhu, HK Wang, YY Qu, DW Ye - Asian journal of andrology, 2015 - journals.lww.com
Prostate cancer is now becoming an emerging health priority in East Asia. Most of our
current knowledge on Prostate cancer has been generated from studies conducted in …

Prevalence and significance of potential drug-drug interactions among cancer patients receiving chemotherapy

M Ismail, S Khan, F Khan, S Noor, H Sajid, S Yar… - BMC cancer, 2020 - Springer
Background Cancer patients often receive multiple drugs to maximize their therapeutic
benefit, treat co-morbidities and counter the adverse effects of chemotherapy. Concomitant …