Modulation of macrophage polarization by viruses: turning off/on host antiviral responses
S Yu, H Ge, S Li, HJ Qiu - Frontiers in microbiology, 2022 - frontiersin.org
Macrophages are professional antigen-presenting cells and serve as the first line of defense
against invading pathogens. Macrophages are polarized toward the proinflammatory …
against invading pathogens. Macrophages are polarized toward the proinflammatory …
IL-8 decreases HIV-1 transcription in peripheral blood lymphocytes and ectocervical tissue explants
C Rollenhagen, SN Asin - JAIDS Journal of Acquired Immune …, 2010 - journals.lww.com
IL-8 is enhanced in the peripheral blood and lymphoid tissue of HIV-infected individuals,
suggesting that IL-8 is important in the pathogenesis of HIV-1 infection and progression to …
suggesting that IL-8 is important in the pathogenesis of HIV-1 infection and progression to …
Virus-Induced Cell Fusion and Syncytia Formation
M Xie - Syncytia: Origin, Structure, and Functions, 2023 - Springer
Most enveloped viruses encode viral fusion proteins to penetrate host cell by membrane
fusion. Interestingly, many enveloped viruses can also use viral fusion proteins to induce cell …
fusion. Interestingly, many enveloped viruses can also use viral fusion proteins to induce cell …
Resistance to Simian HIV infection is associated with high plasma interleukin-8, RANTES and Eotaxin in a macaque model of repeated virus challenges
N Promadej-Lanier, DL Hanson… - JAIDS Journal of …, 2010 - journals.lww.com
Animal models for research on susceptibility to HIV are currently not available. Here we
explore whether a macaque model of repeated low-dose rectal or vaginal virus challenges …
explore whether a macaque model of repeated low-dose rectal or vaginal virus challenges …
The simultaneous presence and expression of human hepatitis C virus (HCV), human herpesvirus-6 (HHV-6), and human immunodeficiency virus-1 (HIV-1) in a single …
SZ Salahuddin, KA Snyder, A Godwin, R Grewal… - Virology Journal, 2007 - Springer
We have developed a system that isolates and replicates HCV in vitro. These isolates are
called CIMM-HCV. This system has made it possible to analyze the biology, nature, and …
called CIMM-HCV. This system has made it possible to analyze the biology, nature, and …
Human herpesvirus 6B U19 protein is a PML-regulated transcriptional activator that localizes to nuclear foci in a PML-independent manner
E Kofod-Olsen, K Ross-Hansen… - Journal of general …, 2008 - microbiologyresearch.org
Human herpesvirus 6B (HHV-6B) contains an IE-B domain spanning open reading frames
U16/17–U19, based on homology with human cytomegalovirus. Here, the protein product …
U16/17–U19, based on homology with human cytomegalovirus. Here, the protein product …
The immunological role of cell wall components from diverse Mycobacterium tuberculosis clinical isolates in regulating HIV-1 replication in human macrophages
M Ndengane - 2023 - open.uct.ac.za
Human immunodeficiency virus type 1 (HIV-1) and Mycobacterium tuberculosis (Mtb)
coinfection remains a major global health threat. Both pathogens synergistically drive …
coinfection remains a major global health threat. Both pathogens synergistically drive …
HIV‐1 Replication in HIV‐Infected Individuals Is Significantly Reduced When Peripheral Blood Mononuclear Cells Are Superinfected with HSV‐1
T Yamsuwan, C Chirathaworn… - The Scientific World …, 2012 - Wiley Online Library
Herpes simplex virus (HSV) can cause generalized infection in human immunodeficiency
virus‐(HIV‐) infected patients leading to death. This study investigated HSV‐1 replication in …
virus‐(HIV‐) infected patients leading to death. This study investigated HSV‐1 replication in …
Platinum (IV) compounds targeting zinc finger domains
H Kay - US Patent 8,895,610, 2014 - Google Patents
US PATENT DOCUMENTS Retrovirology, 2009, 6: 50. Anzellotti et al., Zinc metalloproteins
as medicinal targets, Chem. 4,716, 157 A 12/1987 Bitha et al. Soc. Reb. 2008, 37, pp. 1629 …
as medicinal targets, Chem. 4,716, 157 A 12/1987 Bitha et al. Soc. Reb. 2008, 37, pp. 1629 …
Lipid raft, caveolin protein, and caveolar function modulation compounds and associated synthetic and therapeutic methods
H Kay - US Patent 8,026,382, 2011 - Google Patents
The present invention is directed to the modulation of lipid rafts, caveolin proteins, or
caveolar functions and processes by platinum (IV) compounds. Caveolae and/or lipid rafts …
caveolar functions and processes by platinum (IV) compounds. Caveolae and/or lipid rafts …