Glaucoma and the brain: trans-synaptic degeneration, structural change, and implications for neuroprotection

M Lawlor, H Danesh-Meyer, LA Levin… - Survey of …, 2018 - Elsevier
A recent hypothesis to enter the literature suggests that glaucoma is a neurodegenerative
disease. The basis for this has been the finding of central nervous system changes in …

Using magnetic resonance imaging to assess visual deficits: a review

HDH Brown, RL Woodall, RE Kitching… - Ophthalmic and …, 2016 - Wiley Online Library
Purpose Over the last two decades, magnetic resonance imaging (MRI) has been widely
used in neuroscience research to assess both structure and function in the brain in health …

Voxel-based morphometry and diffusion tensor imaging of the optic pathway in primary open-angle glaucoma: a preliminary study

AK Zikou, G Kitsos, LC Tzarouchi… - American Journal …, 2012 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Neuropathologic studies in experimental and human
glaucoma have demonstrated degenerative changes in the optic pathway. The purpose of …

Lipid composition of the human eye: are red blood cells a good mirror of retinal and optic nerve fatty acids?

N Acar, O Berdeaux, S Gregoire, S Cabaret, L Martine… - PloS one, 2012 - journals.plos.org
Background The assessment of blood lipids is very frequent in clinical research as it is
assumed to reflect the lipid composition of peripheral tissues. Even well accepted such …

Automated morphometry of the visual pathway in primary open-angle glaucoma

AT Hernowo, CC Boucard… - … & visual science, 2011 - iovs.arvojournals.org
Purpose.: To establish whether primary open-angle glaucoma (POAG) is associated with a
change in volume of the visual pathway structures between the eyes and the visual cortex …

Structural brain MRI studies in eye diseases: are they clinically relevant? A review of current findings

D Prins, S Hanekamp, FW Cornelissen - Acta ophthalmologica, 2016 - Wiley Online Library
Many eye diseases reduce visual acuity or are associated with visual field defects. Because
of the well‐defined retinotopic organization of the connections of the visual pathways, this …

Anterior visual pathway assessment by magnetic resonance imaging in normal‐pressure glaucoma

YQ Zhang, J Li, L Xu, L Zhang, ZC Wang… - Acta …, 2012 - Wiley Online Library
Purpose: To analyze the axonal architecture of the optic nerve in patients with normal‐
pressure glaucoma and determine whether these parameters correlate with the disease …

Evidence for widespread structural brain changes in glaucoma: a preliminary voxel-based MRI study

AL Williams, J Lackey, SS Wizov… - … & visual science, 2013 - iovs.arvojournals.org
Methods.: High-resolution T1-weighted anatomical brain magnetic resonance images (MRI)
were collected in 15 patients with glaucoma of varying severity and in 15 age-, race-, and …

[HTML][HTML] Morphometry of the retrobulbar human optic nerve: comparison between conventional sonography and ultrafast magnetic resonance sequences

WA Lagreze, A Lazzaro, M Weigel… - … & visual science, 2007 - arvojournals.org
purpose. To compare different methods for quantification of optic nerve and nerve sheath
diameter. To apply a novel magnetic resonance protocol using half-Fourier acquired single …

Differentiation of compressive from glaucomatous optic neuropathy with spectral-domain optical coherence tomography

HV Danesh-Meyer, J Yap, C Frampton, PJ Savino - Ophthalmology, 2014 - Elsevier
Purpose To compare optic disc topography in eyes with compressive optic neuropathy
(CON) and open-angle glaucoma (OAG) using spectral-domain (SD) optical coherence …