[HTML][HTML] Epidemiology of ovarian cancer: a review

BM Reid, JB Permuth, TA Sellers - Cancer biology & medicine, 2017 - ncbi.nlm.nih.gov
Ovarian cancer (OC) is the seventh most commonly diagnosed cancer among women in the
world and the tenth most common in China. Epithelial OC is the most predominant …

Mucinous ovarian carcinoma

P Morice, S Gouy, A Leary - New England Journal of Medicine, 2019 - Mass Medical Soc
Mucinous Ovarian Cancer Mucinous ovarian cancer accounts for 3% of epithelial ovarian
cancers and must be distinguished from mucinous carcinomas that have metastasized to the …

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

CM Phelan, KB Kuchenbaecker, JP Tyrer, SP Kar… - Nature …, 2017 - nature.com
To identify common alleles associated with different histotypes of epithelial ovarian cancer
(EOC), we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC …

Mechanisms of long non-coding RNAs in cancers and their dynamic regulations

XZ Zhang, H Liu, SR Chen - Cancers, 2020 - mdpi.com
Long non-coding RNA (lncRNA), which is a kind of noncoding RNA, is generally
characterized as being more than 200 nucleotide transcripts in length. LncRNAs exhibit …

The molecular origin and taxonomy of mucinous ovarian carcinoma

D Cheasley, MJ Wakefield, GL Ryland, PE Allan… - Nature …, 2019 - nature.com
Mucinous ovarian carcinoma (MOC) is a unique subtype of ovarian cancer with an uncertain
etiology, including whether it genuinely arises at the ovary or is metastatic disease from …

The role of HOX transcription factors in cancer predisposition and progression

B Li, Q Huang, GH Wei - Cancers, 2019 - mdpi.com
Homeobox (HOX) transcription factors, encoded by a subset of homeodomain superfamily
genes, play pivotal roles in many aspects of cellular physiology, embryonic development …

A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants

A Gusev, K Lawrenson, X Lin, PC Lyra Jr, S Kar… - Nature …, 2019 - nature.com
We sought to identify susceptibility genes for high-grade serous ovarian cancer (HGSOC) by
performing a transcriptome-wide association study of gene expression and splice junction …

The DNA methylome of cervical cells can predict the presence of ovarian cancer

JE Barrett, A Jones, I Evans, D Reisel, C Herzog… - Nature …, 2022 - nature.com
The vast majority of epithelial ovarian cancer arises from tissues that are embryologically
derived from the Müllerian Duct. Here, we demonstrate that a DNA methylation signature in …

GWAS in cancer: progress and challenges

B Liang, H Ding, L Huang, H Luo, X Zhu - Molecular Genetics and …, 2020 - Springer
The genome-wide association study (GWAS) is an effective method to detect single-
nucleotide polymorphisms (SNPs) of multiple individual genes based on linkage …

Genetic epidemiology of ovarian cancer and prospects for polygenic risk prediction

MR Jones, D Kamara, BY Karlan, PDP Pharoah… - Gynecologic …, 2017 - Elsevier
Epithelial ovarian cancer (EOC) is a heterogeneous disease with a major heritable
component. The different histotypes of invasive disease–high grade serous, clear cell …