Keloids constitute an abnormal fibroproliferative wound healing response in which raised
scar tissue grows excessively and invasively beyond the original wound borders. This …

Wound repair is a complex biologic process which becomes abnormal in numerous disease
states. Although in vitro models have been important in identifying critical repair pathways in …

Background Hypertrophic scar (HS) is a fibro-proliferative disorder of dermis after burn or
trauma and usually leads to esthetic disfiguration and functionary impairment for patients …

Excessive scar formation has adverse physiological and psychological effects on patients;
therefore, a therapeutic strategy for rapid wound healing and reduced scar formation is …

Cutaneous wound healing in the pig is frequently used as a model for human cutaneous
wound healing. In this review, we examine the appropriateness of this model for studying …

Dermal substitutes are of major importance in treating full thickness skin defects, both in
acute and chronic wounds. We outlined specific requirements of three classes of dermal …

Skin wound healing is essential to health and survival. Consequently, high amounts of
research effort have been put into investigating the cellular and molecular components …

Objective: To test the hypothesis that the mechanical environment of cutaneous wounds can
control scar formation. Background: Mechanical forces have been recognized to modulate …

BACKGROUND: Scar formation following skin trauma can have devastating consequences
causing physiological and psychosocial concerns. Currently, there are no accepted …

The process of repair of wounded skin involves intricate orchestration not only between the
epidermal and dermal compartments but also between the resident and immigrant cells and …