There is increasing evidence that an ongoing cytokine-induced acute-phase response
(sometimes called low-grade inflammation, but part of a widespread activation of the innate …

This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …

Insulin resistance is increasingly recognized as a chronic, low-level, inflammatory state.
Hyperinsulinemia and insulin action were initially proposed as the common preceding …

Liver fat deposition related to systemic insulin resistance defines non-alcoholic fatty liver
disease (NAFLD) which, when associated with oxidative hepatocellular damage …

Subclinical, low-grade systemic inflammation has been observed in patients with type 2
diabetes and in those at increased risk of the disease. This may be more than an …

Loos RJF, Bouchard C (Human Genomics Laboratory, Pennington Biomedical Research
Center, Baton Rouge, LA, USA). Obesity–is it a genetic disorder?(Review). J Intern Med …

Immune disorders are linked to the development of type 2 diabetes (T2D) and its
complications. The relationship of CD4+ CD25 hi T regulatory cells (Treg) and pro …

Psoriasis is a chronic and debilitating inflammatory disease associated with serious
comorbidities. Psoriasis can have a significant impact on a patient's quality of life and is …

OBJECTIVE In epidemiological studies, serum ferritin was the second-strongest determinant
of blood glucose (after BMI) in regression models and the third-strongest determinant of …

Obesity represents one of the most serious global health issues with∼ 310 million people
presently affected. It develops because of a mismatch between energy intake and …