Recent advances in the monitoring, modelling and control of crystallization systems
Crystallization is one of the most important unit operations used for the separation and
purification of crystalline solid products. Appropriate design and control of the crystallization …
purification of crystalline solid products. Appropriate design and control of the crystallization …
[HTML][HTML] Applications of machine vision in pharmaceutical technology: A review
DL Galata, LA Meszaros, N Kallai-Szabo… - European Journal of …, 2021 - Elsevier
The goal of this paper is to give an introduction to analysis of images acquired by a digital
camera with visible illumination and to review its applications as a Process Analytical …
camera with visible illumination and to review its applications as a Process Analytical …
Assessment of recent process analytical technology (PAT) trends: a multiauthor review
This multiauthor review article aims to bring readers up to date with some of the current
trends in the field of process analytical technology (PAT) by summarizing each aspect of the …
trends in the field of process analytical technology (PAT) by summarizing each aspect of the …
In Situ Imaging Combined with Deep Learning for Crystallization Process Monitoring: Application to Cephalexin Production
The online detection of a trace amount of an undesired solid phase within a crystal slurry
can enable feedback control to improve product purity, decrease batch rejection, and …
can enable feedback control to improve product purity, decrease batch rejection, and …
Crystal growth measurement using 2D and 3D imaging and the perspectives for shape control
XZ Wang, KJ Roberts, C Ma - Chemical Engineering Science, 2008 - Elsevier
Crystals are particles structured with multiple facets that often have different surface
chemistry and hence varied growth rates during crystallisation. It is possible to manipulate …
chemistry and hence varied growth rates during crystallisation. It is possible to manipulate …
Comparison of external bulk video imaging with focused beam reflectance measurement and ultra-violet visible spectroscopy for metastable zone identification in food …
The purpose of the paper is twofold: it describes the proof of concept of the newly introduced
bulk video imaging (BVI) method and it presents the comparison with existing process …
bulk video imaging (BVI) method and it presents the comparison with existing process …
Crystal shape control by manipulating supersaturation in batch cooling crystallization
G Yang, N Kubota, Z Sha, M Louhi-Kultanen… - Crystal growth & …, 2006 - ACS Publications
This paper describes a study on the shape control of potassium dihydrogen phosphate
(KDP) in batch cooling suspension crystallization by selecting the supersaturation as a …
(KDP) in batch cooling suspension crystallization by selecting the supersaturation as a …
Nucleation of butyl paraben in different solvents
H Yang, ÅC Rasmuson - Crystal growth & design, 2013 - ACS Publications
The primary nucleation induction time of butyl paraben in pure solvents: acetone, ethyl
acetate, methanol, ethanol, and propanol and in 70% and 90% ethanol aqueous mixtures …
acetate, methanol, ethanol, and propanol and in 70% and 90% ethanol aqueous mixtures …
Endoscopy-based in situ bulk video imaging of batch crystallization processes
External bulk video imaging (eBVI) of crystallization processes has proven to be a promising
technique for metastable zone determination. In this contribution the endoscopy-based in …
technique for metastable zone determination. In this contribution the endoscopy-based in …
Sensor Fusion and Calibration-Based Adaptive Image Analysis Procedure for In Situ Crystal Size Measurement
WL Wu, MM Mills, U Schacht, C Rabinowitz… - Crystal Growth & …, 2023 - ACS Publications
Traditionally, off-line measurements via image analysis or laser diffraction methods are used
to analyze the crystal product. It is often beneficial to extract crystal samples intermittently …
to analyze the crystal product. It is often beneficial to extract crystal samples intermittently …