Energy metabolism of the brain, including the cooperation between astrocytes and neurons, especially in the context of glycogen metabolism

A Falkowska, I Gutowska, M Goschorska… - International journal of …, 2015 - mdpi.com
Glycogen metabolism has important implications for the functioning of the brain, especially
the cooperation between astrocytes and neurons. According to various research data, in a …

Axonal degeneration during aging and its functional role in neurodegenerative disorders

N Salvadores, M Sanhueza, P Manque… - Frontiers in …, 2017 - frontiersin.org
Aging constitutes the main risk factor for the development of neurodegenerative diseases.
This represents a major health issue worldwide that is only expected to escalate due to the …

Antidiabetic and Antioxidant Effects and Phytochemicals of Mulberry Fruit (Morus alba L.) Polyphenol Enhanced Extract

Y Wang, L Xiang, C Wang, C Tang, X He - PloS one, 2013 - journals.plos.org
The antidiabetic and antioxidant activities of the ethyl acetate-soluble extract (MFE) of
mulberry fruit (Morus alba L.) were investigated. In vitro, MFE showed potent α-glucosidase …

Anti-diabetic potential of plant alkaloids: Revisiting current findings and future perspectives

H Rasouli, R Yarani, F Pociot… - Pharmacological …, 2020 - Elsevier
Diabetes mellitus (DM) is a chronic metabolic disease which causes millions of death all
over the world each year, and its incidence is on increase. The most prevalent form, type 2 …

Impact of glucose metabolism on the developing brain

M Cacciatore, EA Grasso, R Tripodi… - Frontiers in …, 2022 - frontiersin.org
Glucose is the most important substrate for proper brain functioning and development, with
an increased glucose consumption in relation to the need of creating new brain structures …

Diabetes mellitus-related dysfunction of the motor system

K Muramatsu - International journal of molecular sciences, 2020 - mdpi.com
Although motor deficits in humans with diabetic neuropathy have been extensively
researched, its effect on the motor system is thought to be lesser than that on the sensory …

[HTML][HTML] Defective axonal transport: a common pathological mechanism in inherited and acquired peripheral neuropathies

R Prior, L Van Helleputte, V Benoy… - Neurobiology of …, 2017 - Elsevier
Peripheral neuropathies are characterized by a progressive and length-dependent loss of
peripheral nerve function. This can be caused either by genetic defects, classified as …

Inhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinase

GA Morfini, DA Bosco, H Brown, R Gatto, A Kaminska… - PloS one, 2013 - journals.plos.org
Dying-back degeneration of motor neuron axons represents an established feature of
familial amyotrophic lateral sclerosis (FALS) associated with superoxide dismutase 1 …

Astrocytic and microglial response in experimentally induced diabetic rat brain

A Nagayach, N Patro, I Patro - Metabolic brain disease, 2014 - Springer
Diabetes Mellitus is associated with increased risk of cognitive and behavioural disorders
with hitherto undeciphered role of glia. Glia as majority population in brain serve several …

Hypothalamic inflammation in metabolic disorders and aging

A Bhusal, MH Rahman, K Suk - Cellular and molecular life sciences, 2022 - Springer
The hypothalamus is a critical brain region for the regulation of energy homeostasis. Over
the years, studies on energy metabolism primarily focused on the neuronal component of …