Secreted trophic factors of mesenchymal stem cells support neurovascular and musculoskeletal therapies

HR Hofer, RS Tuan - Stem cell research & therapy, 2016 - Springer
Adult mesenchymal stem cells (MSCs) represent a subject of intense experimental and
biomedical interest. Recently, trophic activities of MSCs have become the topic of a number …

Trends in the design of nerve guidance channels in peripheral nerve tissue engineering

V Chiono, C Tonda-Turo - Progress in neurobiology, 2015 - Elsevier
The current trend of peripheral nerve tissue engineering is the design of advanced nerve
guidance channels (NGCs) acting as physical guidance for regeneration of nerves across …

Tissue‐engineered peripheral nerve interfaces

BS Spearman, VH Desai, S Mobini… - Advanced Functional …, 2018 - Wiley Online Library
Research on neural interfaces has historically concentrated on development of systems for
the brain; however, there is increasing interest in peripheral nerve interfaces (PNIs) that …

Novel approaches using mesenchymal stem cells for curing peripheral nerve injuries

F Yousefi, FL Arab, K Nikkhah, H Amiri, M Mahmoudi - Life sciences, 2019 - Elsevier
Peripheral nerve injury (PNI) is a common life-changing disability of peripheral nervous
system with significant socioeconomic consequences. Conventional therapeutic approaches …

Recent perspectives on the synergy of mesenchymal stem cells with micro/nano strategies in peripheral nerve regeneration-a review

M Sharifi, M Kamalabadi-Farahani, M Salehi… - … in Bioengineering and …, 2024 - frontiersin.org
Despite the intrinsic repair of peripheral nerve injury (PNI), it is important to carefully monitor
the process of peripheral nerve repair, as peripheral nerve regeneration is slow and …

The median nerve injury model in pre-clinical research–a critical review on benefits and limitations

G Ronchi, M Morano, F Fregnan, P Pugliese… - Frontiers in Cellular …, 2019 - frontiersin.org
The successful introduction of innovative treatment strategies into clinical practise strongly
depends on the availability of effective experimental models and their reliable pre-clinical …

Stem cells purified from human induced pluripotent stem cell-derived neural crest-like cells promote peripheral nerve regeneration

H Kimura, T Ouchi, S Shibata, T Amemiya, N Nagoshi… - Scientific reports, 2018 - nature.com
Strategies for therapeutic cell transplantation have been assessed for use in the treatment of
massive peripheral nerve defects. To support safe and efficient cell transplantation, we have …

Engineered exosomes: A new promise for the management of musculoskeletal diseases

D Bellavia, L Raimondi, V Costa, A De Luca… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Background Exosomes are nanovesicles actively secreted by potentially all cell types,
including tumour cells, with the primary role of extracellular systemic communication …

Стимуляция регенерации периферического нерва: современное состояние, проблемы и перспективы

ИН Щаницын, АН Иванов, СП Бажанов… - Успехи …, 2017 - elibrary.ru
Повреждение периферических нервов-одна из сложных и нерешенных проблем
клинической медицины, что обусловлено низкой регенеративной способностью …

Lower jaw‐to‐forepaw rapid and delayed reorganization in the rat forepaw barrel subfield in primary somatosensory cortex

V Pellicer‐Morata, L Wang, AJ Curry… - Journal of …, 2023 - Wiley Online Library
We used the forepaw barrel subfield (FBS), that normally receives input from the forepaw
skin surface, in rat primary somatosensory cortex as a model system to study rapid and …